Evidence map›Paper›PMID 39203484›Full record

ReviewMicroorganisms2024

The Role of Postbiotics in Asthma Treatment.

Konstancja Węgrzyn, Agnieszka Jasińska, Kamil Janeczek, Wojciech Feleszko

Abstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Konstancja WęgrzynCentral Clinical Hospital, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0009-0001-3975-4964
Agnieszka JasińskaDepartment of Pediatric Pneumonology and Allergy, University Clinical Centre, Medical University of Warsaw, 02-097 Warsaw, Poland.
Kamil JaneczekDepartment of Paediatric Pulmonology and Rheumatology, Medical University of Lublin, 20-059 Lublin, Poland.ORCID 0000-0002-8163-873X
Wojciech FeleszkoDepartment of Pediatric Pneumonology and Allergy, University Clinical Centre, Medical University of Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0001-6613-2012

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, there has been abundant research concerning human microbiome and its impact on the host's health. Studies have shown that not only the commensal bacteria itself, but also postbiotics, understood as inanimate microorganisms, possibly with the presence of their components, may themselves have an effect on various elements of human physiology. In this review, we take a closer look at the specific ways in which postbiotics can alter immune response in allergic asthma, which is one of the most prevalent allergic diseases in today's world and a serious subject of concern. Through altering patients' immune response, not only to allergens but also to pathogens, postbiotics could have a significant role in lowering the number of asthma exacerbations. We suggest that more profound research should be undertaken in order to launch postbiotics into clinical standards of asthma treatment, given the greatly promising findings in terms of their immunomodulating potential.

Indexed as

allergic asthmabacterial lysatesimmunomodulationmicrobiomepostbiotics

Identifiers

PMID39203484
PMCPMC11356534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.