Evidence map›Paper›PMID 39202907›Full record

ReviewMolecules (Basel, Switzerland)2024

Macrocycle-Based Supramolecular Drug Delivery Systems: A Concise Review.

Yanrui Yang, Pengcheng Li, Haibo Feng, Rui Zeng, Shanshan Li, Qixiong Zhang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Stabilization of 5-aminolevulinic acid by cucurbit[7]uril complex with enhanced fluorescence detection and photodynamic therapy of breast cancer in vitro and in a CAM model.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanrui YangCollege of Pharmacy, Key Laboratory of Research and Application of Ethnic Medicine Processing and Preparation on the Qinghai Tibet Plateau, Southwest Minzu University, Chengdu 610041, China.
Pengcheng LiCollege of Pharmacy, Key Laboratory of Research and Application of Ethnic Medicine Processing and Preparation on the Qinghai Tibet Plateau, Southwest Minzu University, Chengdu 610041, China.
Haibo FengCollege of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu 610041, China.
Rui ZengCollege of Pharmacy, Key Laboratory of Research and Application of Ethnic Medicine Processing and Preparation on the Qinghai Tibet Plateau, Southwest Minzu University, Chengdu 610041, China.
Shanshan LiCollege of Pharmacy, Key Laboratory of Research and Application of Ethnic Medicine Processing and Preparation on the Qinghai Tibet Plateau, Southwest Minzu University, Chengdu 610041, China.
Qixiong ZhangDepartment of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China.ORCID 0000-0003-0330-1389

Funding

National Natural Science Foundation of China 82204304National Training Program of Innovation and Entrepreneurship for Undergraduates 202310656039Natural Science Foundation of Sichuan 2023NSFSC1678Open Project of Personalized Drug Therapy Key Laboratory of Sichuan Province 2022YB01Southwest Minzu University Research Startup Funds RQD2022033Youth Innovation Project of Sichuan Medical Association Q22006
6 · The paper itself

Abstract

Efficient delivery of therapeutic agents to the lesion site or specific cells is an important way to achieve "toxicity reduction and efficacy enhancement". Macrocycles have always provided many novel ideas for drug or gene loading and delivery processes. Specifically, macrocycles represented by crown ethers, cyclodextrins, cucurbit[n]urils, calix[n]arenes, and pillar[n]arenes have unique properties, which are different cavity structures, good biocompatibility, and good stability. Benefited from these diverse properties, a variety of supramolecular drug delivery systems can be designed and constructed to effectively improve the physical and chemical properties of guest molecules as needed. This review provides an outlook on the current application status and main limitations of macrocycles in supramolecular drug delivery systems.

Indexed as

Drug Delivery SystemsMacrocyclic CompoundsCalixarenesCrown EthersCyclodextrinsDrug CarriersHumansMacromolecular SubstancesCalixarenesCrown EthersCyclodextrinsDrug CarriersMacrocyclic CompoundsMacromolecular Substancesbioavailabilitydrug delivery systemshost–guest interactionmacrocyclic compoundssupramolecular chemistry

Identifiers

PMID39202907
PMCPMC11357536

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.