Evidence map›Paper›PMID 39202897›Full record

ArticleMolecules (Basel, Switzerland)2024

Slowing Down the "Magic Bullet": Encapsulation of Imatinib in Fe-MOF for Cardiotoxicity Reduction and Improvement in Anticancer Activity.

Weronika Strzempek, Elżbieta Menaszek, Monika Papież, Barbara Gil

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Weronika StrzempekFaculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.
Elżbieta MenaszekFaculty of Pharmacy, Jagiellonian University Collegium Medicum, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0002-0602-3583
Monika PapieżFaculty of Pharmacy, Jagiellonian University Collegium Medicum, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0002-2196-3573
Barbara GilFaculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387 Kraków, Poland.ORCID 0000-0003-4096-0762

Funding

National Science Center 2014/15/B/ST5/04498
6 · The paper itself

Abstract

Imatinib, a small molecule kinase inhibitor, is used as a cancer growth blocker. However, one of its most serious side effects is congestive cardiac failure. Reducing drug toxicity may be achieved through the use of drug delivery systems. Biocompatible metal-organic framework (MOF) materials, namely FeMIL-100 and FeMIL-101-NH

Indexed as

Antineoplastic AgentsDrug CarriersImatinib MesylateMetal-Organic FrameworksAnimalsCardiotoxicityCell SurvivalDrug LiberationHL-60 CellsHumansHydrogen-Ion ConcentrationAntineoplastic AgentsDrug CarriersImatinib MesylateMetal-Organic Frameworkscardiotoxicity inhibitiondrug deliveryFeMIL-100FeMIL-101-NH2imatiniblymphoblastic leukemiametal-organic frameworks

Identifiers

PMID39202897
PMCPMC11357391

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.