Evidence map›Paper›PMID 39202875›Full record

ArticleMolecules (Basel, Switzerland)2024

Selectivity Screening and Structure-Cytotoxic Activity Observations of Selected Oleanolic Acid (OA)-Type Saponins from the Amaranthaceae Family on a Wiade Panel of Human Cancer Cell Lines.

Karolina Grabowska, Agnieszka Galanty, Łukasz Pecio, Anna Stojakowska, Janusz Malarz, Paweł Żmudzki, Paweł Zagrodzki, Irma Podolak

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Food & nutrition research · 2026
    Article
  5. Saponins fromMolecules (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karolina GrabowskaDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0002-1426-2218
Agnieszka GalantyDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0001-5636-8646
Łukasz PecioDepartment of Biochemistry and Crop Quality, Institute of Soil Science and Plant Cultivation-State Research Institute, ul. Czartoryskich 8, 24-100 Puławy, Poland.ORCID 0000-0002-7407-6716
Anna StojakowskaMaj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.ORCID 0000-0001-9242-2072
Janusz MalarzMaj Institute of Pharmacology, Polish Academy of Sciences, Smętna Street 12, 31-343 Kraków, Poland.ORCID 0000-0001-5668-5940
Paweł ŻmudzkiDepartment of Medicinal Chemistry, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0003-3594-1241
Paweł ZagrodzkiDepartment of Food Chemistry and Nutrition, Jagiellonian University Medical College, 9 Medyczna, 30-688 Kraków, Poland.ORCID 0000-0002-5101-036X
Irma PodolakDepartment of Pharmacognosy, Jagiellonian University Medical College, 9 Medyczna Str., 30-688 Cracow, Poland.ORCID 0000-0002-1251-7192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants from the Amaranthaceae family are a source of oleanolic acid (OA)-type saponins with cytotoxic activity. Two known OA-type saponins, calenduloside E and chikusetsusaponin IVa, were isolated from the roots of

Indexed as

Antineoplastic Agents, PhytogenicOleanolic AcidSaponinsAmaranthaceaeCell Line, TumorCell ProliferationCell SurvivalDrug Screening Assays, AntitumorHumansMolecular StructurePlant ExtractsStructure-Activity RelationshipAntineoplastic Agents, PhytogenicOleanolic AcidPlant ExtractsSaponinscalenduloside EChenopodium strictumchikusetsusaponin IVacytotoxicmomordin Icsaponinsstructure–activity

Identifiers

PMID39202875
PMCPMC11357256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.