Evidence map›Paper›PMID 39202830›Full record

ArticleMolecules (Basel, Switzerland)2024

A New Class of Benzo[

Giovanna Lucia Delogu, Michela Begala, Maria João Matos, Davide Crucitti, Valeria Sogos, Benedetta Era, Antonella Fais

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giovanna Lucia DeloguDepartment of Live and Environmental Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Italy.ORCID 0000-0003-0307-1544
Michela BegalaDepartment of Live and Environmental Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Italy.ORCID 0000-0002-8213-2335
Maria João MatosDepartamento de Química Orgánica, Facultad de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0002-3470-8299
Davide CrucittiGroup of Computational Genomics and Hematology (GreCoXen), Health Research Institute of Santiago de Compostela (IDIS), 15782 Santiago de Compostela, Spain.ORCID 0009-0006-9458-9793
Valeria SogosDepartment of Biomediacal Science, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Italy.ORCID 0000-0002-4021-1043
Benedetta EraDepartment of Live and Environmental Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Italy.ORCID 0000-0002-4154-9740
Antonella FaisDepartment of Live and Environmental Sciences, University of Cagliari, Cittadella Universitaria, SS 554, Km 4.5, 09042 Monserrato, Italy.ORCID 0000-0002-3009-4226

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, heterocyclic compounds containing a benzothiophene scaffold were designed and synthetized, and their inhibitory activity against cholinesterases (ChE) and the viability of SH-SY5Y cells have been evaluated. Benzothiophenes

Indexed as

AcetylcholinesteraseButyrylcholinesteraseChalconesCholinesterase InhibitorsMolecular Docking SimulationThiophenesCell Line, TumorHumansMolecular StructureStructure-Activity RelationshipAcetylcholinesterasebenzothiopheneButyrylcholinesteraseChalconesCholinesterase InhibitorsThiophenesbenzothiophenescholinesterase inhibitorsheterocycles

Identifiers

PMID39202830
PMCPMC11356821

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.