Evidence map›Paper›PMID 39202764›Full record

ArticleLife (Basel, Switzerland)2024

Can Gentisic Acid Serve as a High-Performance Antioxidant with Lower Toxicity for a Promising New Topical Application?

Luciano B Cunha, Eloah D Lepore, Camila Cristina B Medeiros, Rodrigo Sorrechia, Rosemeire C L R Pietro, Marcos A Corrêa

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. LC-ESI-MS/MS Analysis ofMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Metabolomic and Pharmacological Approaches for Exploring the Potential ofInternational journal of molecular sciences · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luciano B CunhaSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.ORCID 0000-0001-5310-6878
Eloah D LeporeSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.ORCID 0000-0003-3800-9409
Camila Cristina B MedeirosSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.
Rodrigo SorrechiaSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.ORCID 0000-0002-0920-7580
Rosemeire C L R PietroSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.ORCID 0000-0001-7859-8127
Marcos A CorrêaSchool of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara 14800-903, Brazil.ORCID 0000-0001-9229-3039

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.636327
6 · The paper itself

Abstract

Gentisic acid (2,5-dihydroxybenzoic acid) is primarily found naturally in plants and has demonstrated a significant range of biological activities; however, its efficacy and safety as a topical application ingredient are not yet well established. Thus, the compound's potential antioxidant and antimicrobial properties were evaluated for efficacy, while the cytotoxicity was evaluated for safety. The antioxidant activity, measured by the DPPH kinetic method, showed an Efficiency Concentration (EC

Indexed as

2,5-dihydroxybenzoic acidantimicrobialantioxidantCandida albicansCutibacterium acnescytotoxicDPPHEscherichia coligentisic acidNRUStaphylococcus aureustopical administration

Identifiers

PMID39202764
PMCPMC11355177

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.