Evidence map›Paper›PMID 39202736›Full record

ArticleLife (Basel, Switzerland)2024

Anti-Cataract Effect of the Traditional Aqueous Extract of Yerba Mate (

Seyma Oncu, Merve Becit-Kizilkaya, Abdulkadir Bilir, Alperen Saritas, Evrim Suna Arikan-Soylemez, Halit Bugra Koca, Fatma Firat, Afife Busra Ugur-Kaplan, Mustafa Abdullah Yilmaz

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Frontiers in chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Seyma OncuDepartment of Medical Pharmacology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.ORCID 0000-0003-2468-2416
Merve Becit-KizilkayaDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.ORCID 0000-0002-8084-4419
Abdulkadir BilirDepartment of Anatomy, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.
Alperen SaritasDepartment of Anatomy, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.ORCID 0000-0003-3523-1936
Evrim Suna Arikan-SoylemezDepartment of Medical Biology, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.
Halit Bugra KocaDepartment of Biochemistry, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.ORCID 0000-0002-5353-3228
Fatma FiratDepartment of Histology and Embryology, Medicine Faculty, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Turkey.ORCID 0000-0003-0027-5138
Afife Busra Ugur-KaplanDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Ataturk University, Erzurum 25240, Turkey.
Mustafa Abdullah YilmazDepartment of Analytical Chemistry, Faculty of Pharmacy, Dicle University, Diyarbakir 21280, Turkey.ORCID 0000-0002-4090-7227

Funding

Afyonkarahisar Health Science University Scientific Research Projects Coordination Unit 22.CAREER.008
6 · The paper itself

Abstract

introductionThe therapeutic effect of different doses of the traditional aqueous extract of dried leaves of yerba mate ( METHODS AND

resultsLC-MS/MS analysis allowed the identification and quantification of 53 metabolites. In the hydrocortisone-induced cataract model, lenses were examined morphologically after treatment and parameters related to oxidative stress (total antioxidant/oxidant status (TAS/TOS), glutathione (GSH), and malondialdehyde (MDA)) were evaluated. Antiproliferative cell nuclear antigen (PCNA) and caspase-3 H-scores were determined and crystallin alpha A (

conclusionYM, which is becoming increasingly popular as a traditional tea, showed a therapeutic effect on hydrocortisone-induced cataracts in chicken embryos at relatively low doses.

Indexed as

cataractchick embryoCRYAAIlex paraguariensisyerba mate

Identifiers

PMID39202736
PMCPMC11355064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.