Evidence map›Paper›PMID 39202411›Full record

ArticleGenes2024

Analyzing Runs of Homozygosity Reveals Patterns of Selection in German Brown Cattle.

Anna Wirth, Jürgen Duda, Reiner Emmerling, Kay-Uwe Götz, Franz Birkenmaier, Ottmar Distl

Abstract read
In one paragraph

Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna WirthInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover (Foundation), 30559 Hannover, Germany.
Jürgen DudaLandeskuratorium der Erzeugerringe für Tierische Veredelung in Bayern e.V. (LKV), 80687 München, Germany.
Reiner EmmerlingBavarian State Research Center for Agriculture, Institute of Animal Breeding, 85586 Poing-Grub, Germany.ORCID 0009-0002-0668-5197
Kay-Uwe GötzBavarian State Research Center for Agriculture, Institute of Animal Breeding, 85586 Poing-Grub, Germany.ORCID 0000-0001-5495-7738
Franz BirkenmaierAmt für Ernährung, Landwirtschaft und Forsten, 87439 Kempten, Germany.
Ottmar DistlInstitute of Animal Breeding and Genetics, University of Veterinary Medicine Hannover (Foundation), 30559 Hannover, Germany.ORCID 0000-0002-3516-836X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing trend in ancestral and classical inbreeding coefficients as well as inbreeding depression for longevity were found in the German Brown population. In addition, the proportion of US Brown Swiss genes is steadily increasing in German Browns. Therefore, the aim of the present study was to analyze the presence and genomic localization of runs of homozygosity (ROH) in order to evaluate their associations with the proportion of US Brown Swiss genes and survival rates of cows to higher lactations. Genotype data were sampled in 2364 German Browns from 258 herds. The final data set included 49,693 autosomal SNPs. We identified on average 35.996 ± 7.498 ROH per individual with a mean length of 8.323 ± 1.181 Mb. The genomic inbreeding coefficient F

Indexed as

HomozygoteInbreedingPolymorphism, Single NucleotideSelection, GeneticAnimalsCattleFemaleGenotypeGermanyLactationLongevityeffective population sizegenomic inbreedingoriginal brownruns of homozygosity islandssurvivalUS Brown Swiss

Identifiers

PMID39202411
PMCPMC11354284

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.