ArticleGenes2024
Integrated Metagenomic and Metabolomics Profiling Reveals Key Gut Microbiota and Metabolites Associated with Weaning Stress in Piglets.
Article in Genes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Microbial regulation of intestinal stem cell function: implications for alleviating intestinal injury of weaned piglets.NPJ biofilms and microbiomes · 2026Review
- Bacteria and phage consortia modulate cecal SCFA production and host metabolism to enhance feed efficiency in ducks.Microbiome · 2026Article
- Article
- Linking the degree of intrauterine growth restriction to alterations in metabolism, energy reserves, and gut health in newborn piglets.Journal of animal science · 2026Article
- DietaryFrontiers in veterinary science · 2026Article
- The Role of Swine Gut Microbiota and Its Metabolites in Maintaining Intestinal Barrier Integrity and Mitigating Stress via the Gut-Brain Axis.Animals : an open access journal from MDPI · 2025Review
- Age-related evolution of serum biochemistry and intestinal fatty acid signaling, innate immune response, and barrier function in suckling and newly weaned piglets.Journal of animal science · 2025Article
- Comparison of fecal microbiota and metabolites in diarrheal piglets pre-and post-weaning.Frontiers in veterinary science · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
(1) Background: Weaning is a challenging and stressful event in the pig's life, which disrupts physiological balance and induces oxidative stress. Microbiota play a significant role during the weaning process in piglets. Therefore, this study aimed to investigate key gut microbiota and metabolites associated with weaning stress in piglets. (2) Methods: A total of ten newborn piglet littermates were randomly assigned to two groups: S (suckling normally) and W (weaned at 21 d; all euthanized at 23 d). Specimens of the cecum were dehydrated with ethanol, cleared with xylene, embedded in paraffin, and cut into 4 mm thick serial sections. After deparaffinization, the sections were stained with hematoxylin and eosin (H&E) for morphometric analysis. Cecal metagenomic and liver LC-MS-based metabolomics were employed in this study. Statistical comparisons were performed by a two-tailed Student's
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Registered trials
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