Evidence map›Paper›PMID 39202320›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Severe Liver Damage in an Obese Patient: Onset of Celiac Disease or Overlap Syndrome?

Gabriela Ghiga, Laura Otilia Boca, Elena Cojocaru, Iuliana Magdalena Stârcea, Elena Țarcă, Ana Maria Scurtu, Maria Adriana Mocanu, Ileana Ioniuc, Mihaela Camelia Tîrnovanu, Laura Mihaela Trandafir

Abstract readCase Reports
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gabriela GhigaDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Laura Otilia BocaDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Elena Cojocaru"Saint Mary" Emergency Hospital for Children, 700309 Iasi, Romania.ORCID 0000-0001-7859-840X
Iuliana Magdalena StârceaDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.ORCID 0000-0002-3937-7425
Elena Țarcă"Saint Mary" Emergency Hospital for Children, 700309 Iasi, Romania.ORCID 0000-0002-3018-8011
Ana Maria Scurtu"Saint Mary" Emergency Hospital for Children, 700309 Iasi, Romania.
Maria Adriana MocanuDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Ileana IoniucDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Mihaela Camelia TîrnovanuDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.
Laura Mihaela TrandafirDepartment of Mother and Child, Faculty of Medicine, University of Medicine and Pharmacy "Grigore T Popa", 700115 Iasi, Romania.ORCID 0000-0002-8326-7610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CeD) is an enteropathy caused by the complex interaction between genetic, environmental, and individual immunological factors. Besides the hallmark of intestinal mucosal damage, CeD is a systemic disorder extending beyond the gastrointestinal tract and impacting various other organs, causing extraintestinal and atypical symptoms. The association between CeD and liver damage has been classified into three main categories: mild and asymptomatic liver injury, autoimmune liver injury, and liver failure. We present a case of severe liver damage with cirrhotic evolution in an obese 12-year-old boy who had been admitted due to generalized jaundice and localized abdominal pain in the right hypochondrium. In the course of investigating the etiology of severe liver disease, toxic, infectious, metabolic, obstructive, and genetic causes were excluded. Despite the patient's obesity, a diagnosis of CeD was established, and in accordance with autoimmune hepatitis (AIH) criteria, the patient was diagnosed with autoantibody-negative AIH associated to CeD.

Indexed as

autoimmune hepatitisceliac diseasegluten-free diethepatitisliver disease

Identifiers

PMID39202320
PMCPMC11353973

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.