Evidence map›Paper›PMID 39202063›Full record

ReviewJournal of personalized medicine2024

Advances in the Management of Localized Scleroderma: A Systematic Review of Laser Therapy and Injectable Filler Approaches.

Fortunato Cassalia, Serena Federico, Andrea Danese, Ludovica Franceschin, Simone Amato, Francesco Gratteri, Chiara Battilotti, Francesca Caroppo, Elena Zappia, Luigi Bennardo and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fortunato CassaliaUnit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.ORCID 0000-0002-5014-1122
Serena FedericoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.
Andrea DaneseUnit of Dermatology, Department of Integrated Medical and General Activity, University of Verona, 37100 Verona, Italy.
Ludovica FranceschinUnit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
Simone AmatoDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6336-6187
Francesco GratteriUnit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.
Chiara BattilottiDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0008-1773-3370
Francesca CaroppoUnit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.ORCID 0000-0003-3583-0816
Elena ZappiaDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0009-0005-8167-0325
Luigi BennardoDepartment of Health Sciences, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-0434-1027
Anna Belloni FortinaUnit of Dermatology, Department of Medicine, University of Padua, 35121 Padua, Italy.ORCID 0000-0001-5791-0775
Steven Paul NisticòDermatology Unit, Department of Clinical Internal Anesthesiologic Cardiovascular Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-3828-0883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Localized scleroderma (LS), commonly known as morphea, presents a significant clinical challenge due to its chronic, inflammatory nature affecting the skin and potentially underlying tissues. This systematic review explores the innovative approach of combining laser therapy and injectable fillers, specifically hyaluronic acid, for the treatment of LS. We conducted a comprehensive literature review following PRISMA guidelines, examining articles from MEDLINE/PubMed to assess the combined efficacy of these treatments in improving both esthetic and functional outcomes for LS patients. The search yielded 64 articles, with six selected for in-depth analysis for a total of nine patients, covering a range of patient demographics and treatment types. Our review highlights cases where fractional CO

Indexed as

CO2 laserdermal fillerdye laserhyaluronic acid fillerslaser therapylocalized sclerodermamorpheasystemic sclerosis

Identifiers

PMID39202063
PMCPMC11355336

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.