Evidence map›Paper›PMID 39202039›Full record

ArticleJournal of personalized medicine2024

Subclinical Ocular Motility Dysfunction and Extraocular Muscle Changes in Inactive Graves' Orbitopathy.

Filippo Lixi, Alberto Cuccu, Giuseppe Giannaccare, Matteo Onnis, Mihaela Madalina Timofte Zorila, Stefano Mariotti, Rosanna Vacca, Paola Elisa Meloni, Michela Pisu, Chiara Mura and 1 more

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Filippo LixiEye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0009-0008-0956-4925
Alberto CuccuEye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0009-0001-0869-2131
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0003-2617-0289
Matteo OnnisEye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, Italy.
Mihaela Madalina Timofte ZorilaDepartment of Ophthalmology, Cai Ferate Clinical Hospital, 1 Garabet Ibraileanu Street, 700506 Iasi, Romania.
Stefano MariottiEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Rosanna VaccaEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Paola Elisa MeloniEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Michela PisuEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Chiara MuraEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.
Francesco BoiEndocrinology Unit, Department of Medical Sciences and Public Health, University of Cagliari, 09124 Cagliari, Italy.ORCID 0000-0002-9924-5192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the presence of structural and functional changes in extraocular muscles (EMs) among patients with inactive Graves' orbitopathy (GO) classified according to the Clinical Activity Score (CAS). Sixty-seven patients with Graves' disease (GD) and inactive GO were included. The data collected included clinical parameters, thyroid function, autoantibody levels, EOM morphology via orbital ultrasound (US), and ocular motility. Patients were stratified into Red Filter Test (RFT)-positive or RFT-negative groups based on the presence or absence of latent diplopia during the RFT examination. Thirty-three patients (49.25%) exhibited latent diplopia on the RFT, despite not reporting double vision during standard ocular motility tests. Significant differences were observed between the two groups in terms of age, disease duration, intraocular pressure (IOP) elevation in up-gaze, and medial rectus muscle thickness (

Indexed as

CASGraves’ orbitopathyRed Filter Testthyroid eye disease

Identifiers

PMID39202039
PMCPMC11355160

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.