Evidence map›Paper›PMID 39202021›Full record

ArticleJournal of personalized medicine2024

Sex as a Predictor of Outcomes for Symptomatic Carotid Stenosis: A Comparative Analysis between CAS and CEA.

Pasqualino Sirignano, Costanza Margheritini, Wassim Mansour, Francesco Aloisi, Carlo Setacci, Francesco Speziale, Eugenio Stabile, Maurizio Taurino, On Behalf Of The Ironguard-Study Investigators

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Article in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Pasqualino SirignanoVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00189 Rome, Italy.ORCID 0000-0002-1312-1915
Costanza MargheritiniVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.
Wassim MansourVascular and Endovascular Surgery Unit, Policlinico Umberto I Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0002-7774-8178
Francesco AloisiVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.ORCID 0000-0001-9890-9199
Carlo SetacciVascular and Endovascuar Surgery Unit, "Le Scotte" Hospital of Siena, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Francesco SpezialeVascular and Endovascular Surgery Unit, Policlinico Umberto I Hospital of Rome, Department of General and Specialistic Surgery, "Sapienza" University of Rome, 00161 Rome, Italy.
Eugenio StabileDivision of Cardiology, Cardiovascular Department, San Carlo Regional Hospital, "Federico II" University of Naples, 85100 Potenza, Italy.
Maurizio TaurinoVascular and Endovascular Surgery Unit, Sant'Andrea Hospital of Rome, Department of Molecular and Clinical Medicine, "Sapienza" University of Rome, 00189 Rome, Italy.ORCID 0000-0001-5853-9410
On Behalf Of The Ironguard-Study Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeReporting gender-related outcomes for symptomatic carotid lesion revascularization after both endarterectomy (CEA) and carotid artery stenting (CAS) procedures in an unselected group of patients treated by Italian Vascular Specialists. MATERIAL AND

methodsA retrospective study was conducted on patients presenting with recently symptomatic carotid stenosis treated by CAS and by CEA. The primary endpoint was the 30 days any stroke occurrence rate; secondary endpoints were technical success, occurrence of transient ischemic attack (TIA), acute myocardial infarction (AMI) and death. Demographic, clinical and procedural data were all noted in order to identify the outcome's determining factor.

resultsA total of 265 patients (193 males and 72 females) were enrolled, and of these 134 (50.5%) underwent CEA and 131 CAS (49.5%). At 30 days, the overall new stroke rate was 3.4% (one fatal), and no TIA, AMI or deaths were observed. Among strokes, seven major and two minor strokes were reported, with six after CEA and three after CAS (

conclusionsOur experience seems to suggest that both CEA and CAS provide safe and effective results in treating patients presenting with symptomatic carotid stenosis. Regardless of the type of revascularization, female sex is an independent risk factor for stroke recurrence after treatment.

Indexed as

carotid artery stentingcarotid endarterectomycarotid revascularizationfemale sexsymptomatic carotid stenosistiming

Identifiers

PMID39202021
PMCPMC11355406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.