Evidence map›Paper›PMID 39201985›Full record

ReviewJournal of personalized medicine2024

Fundus Autofluorescence in Diabetic Retinopathy.

Otilia-Maria Dumitrescu, Mihail Zemba, Daniel Constantin Brănișteanu, Ruxandra Angela Pîrvulescu, Madalina Radu, Horia Tudor Stanca

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Artificial intelligence in diabetic retinopathy: from automated screening to risk-stratified care.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Otilia-Maria DumitrescuDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Mihail ZembaDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Daniel Constantin BrănișteanuDepartment of Ophthalmology, University of Medicine and Pharmacy "Grigore T. Popa", 700115 Iasi, Romania.ORCID 0009-0009-5147-9596
Ruxandra Angela PîrvulescuDepartment of Ophthalmology, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.ORCID 0000-0002-7462-0929
Madalina RaduDepartment of Ophthalmology, "Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Horia Tudor StancaDepartment of Ophthalmology, University of Medicine and Pharmacy "Carol Davila", 050474 Bucharest, Romania.ORCID 0000-0003-2595-6319

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic retinopathy is a leading cause of visual morbidity worldwide. Fundus autofluorescence is a rapid, non-invasive imaging modality that has gained increased popularity in recent years in the multimodal evaluation of diabetic retinopathy and, in particular, of diabetic macular oedema. Acquired using either a fundus camera or the confocal scanning laser ophthalmoscope, short-wavelength and near-infrared autofluorescence are the most used techniques in diabetic retinopathy. In diabetic macular oedema, short-wavelength autofluorescence, in its cystoid pattern, is useful for detecting cystoid macular oedema. Increased spot hyperautofluorescence in short-wavelength and granular changes in near-infrared autofluorescence correlate well with other imaging findings, indicating photoreceptor and retinal pigment epithelium damage and being associated with decreased visual acuity. While also being a marker of oxidative stress, increased short-wavelength autofluorescence in the setting of diabetic macular oedema appears to be a prognostic factor for poor visual outcome, even after the resolution of the intraretinal fluid. Autofluorescence also helps in the assessment of diabetic retinal pigment epitheliopathy and choroidopathy. Fundus autofluorescence is an evolving technology that will assist in gaining further insight into the pathophysiology of diabetic retinopathy and allow for a more comprehensive evaluation of these patients.

Indexed as

diabetic macular oedemadiabetic retinopathyfundus autofluorescence

Identifiers

PMID39201985
PMCPMC11355256

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.