Evidence map›Paper›PMID 39201972›Full record

ReviewJournal of personalized medicine2024

Ocular Implications of COVID-19 Infection and Vaccine-Related Adverse Events.

Uday Pratap Singh Parmar, Pier Luigi Surico, Rohan Bir Singh, Mutali Musa, Anna Scarabosio, Giorgio Surico, Antonino Maniaci, Salvatore Lavalle, Fabiana D'Esposito, Antonio Longo and 3 more

Abstract readReview
In one paragraph

Review in Journal of personalized medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Ocular Symptoms in Long COVID: A Cross-Sectional Study.Clinical ophthalmology (Auckland, N.Z.) · 2026
    Article
  2. Article
  3. Review
  4. COVID-19 pandemic and ophthalmology: insights from the IVORC Academic Foundation.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Uday Pratap Singh ParmarDepartment of Ophthalmology, Government Medical College and Hospital, Chandigarh 160047, India.
Pier Luigi SuricoSchepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-7721-4694
Rohan Bir SinghSchepens Eye Research Institute of Mass Eye and Ear, Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0002-2426-3900
Mutali MusaDepartment of Optometry, University of Benin, Benin City 300238, Nigeria.ORCID 0000-0001-7486-8361
Anna ScarabosioDepartment of Plastic Surgery, University Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0003-2993-8580
Giorgio SuricoMedicine and Surgery Department, University of Bari Aldo Moro, 70126 Bari, Italy.
Antonino ManiaciDepartment of Medicine and Surgery, University of Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.ORCID 0000-0002-1251-0185
Salvatore LavalleDepartment of Medicine and Surgery, University of Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.ORCID 0009-0009-5556-6259
Fabiana D'EspositoImperial College Ophthalmic Research Group (ICORG) Unit, Imperial College, 153-173 Marylebone Rd., London NW1 5QH, UK.ORCID 0000-0002-7938-876X
Antonio LongoFaculty of Medicine, University of Catania, Piazza Università, 95123 Catania, Italy.
Andrea RussoFaculty of Medicine, University of Catania, Piazza Università, 95123 Catania, Italy.
Caterina GaglianoDepartment of Medicine and Surgery, University of Enna "Kore", Piazza dell'Università, 94100 Enna, Italy.ORCID 0000-0001-8424-0068
Marco ZeppieriDepartment of Ophthalmology, University Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0003-0999-5545

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The COVID-19 pandemic, caused by SARS-CoV-2, has significantly impacted various organ systems, including the eyes. Initially considered a primarily respiratory disease, it is now evident that COVID-19 can induce a range of ocular symptoms. Recognizing these ocular manifestations is crucial for eye care practitioners as they can serve as early indicators of the disease. This review consolidates current evidence on the ocular effects of COVID-19, identifying manifestations such as conjunctivitis, scleritis, uveitis, and retinopathy. The increasing prevalence of these symptoms highlights the importance of thorough eye examinations and detailed patient histories in COVID-19 cases. Potential routes of viral entry into ocular tissues and the underlying mechanisms, including direct infection, immune responses, and vascular involvement, are explored. Additionally, this review addresses ocular side effects associated with COVID-19 vaccines, such as corneal graft rejection, uveitis, and retinal issues. These findings emphasize the need for ongoing surveillance and research to ensure vaccine safety.

Indexed as

adaptive immune responseCOVID-19ocular immunityocular inflammationSARS-CoV-2side effectsvaccination

Identifiers

PMID39201972
PMCPMC11355216

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.