Evidence map›Paper›PMID 39201925›Full record

ArticleChildren (Basel, Switzerland)2024

From Pancytopenia to Hyperleukocytosis, an Unexpected Presentation of Immune Reconstitution Inflammatory Syndrome in an Infant with Methylmalonic Acidemia.

Samuel Sassine, Amandine Remy, Tanguy Demaret, François Proulx, Julie Autmizguine, Fatima Kakkar, Thai Hoa Tran, Caroline Laverdière, Ellery T Cunan, Catalina Maftei and 3 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Samuel SassineCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.ORCID 0000-0002-6175-7547
Amandine RemyFaculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Tanguy DemaretFaculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
François ProulxCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Julie AutmizguineCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Fatima KakkarCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Thai Hoa TranCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Caroline LaverdièreCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Ellery T CunanDivision of Pediatric Critical Care, Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, QC H3A 0G4, Canada.
Catalina MafteiFaculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.
Grant MitchellCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Hélène DecaluweCHU Sainte-Justine Research Center, Montreal, QC H3T 1C5, Canada.
Jade HindiéFaculty of Medicine, Université de Montréal, Montreal, QC H3T 1J4, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 2.5-month-old girl admitted for failure to thrive and severe pancytopenia was diagnosed with methylmalonic acidemia (MMA) secondary to transcobalamin II deficiency, an inborn error of vitamin B12 metabolism. Opportunistic Cytomegalovirus and

Indexed as

cytomegalovirushyperleukocytosisimmune reconstitution inflammatory syndromemethylmalonic acidemiapancytopeniaPneumocystis jirovecii

Identifiers

PMID39201925
PMCPMC11352300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.