Evidence map›Paper›PMID 39201886›Full record

ArticleChildren (Basel, Switzerland)2024

Systemic Adverse Events Associated with Locally Administered Corticosteroids.

Femke De Vleeschhauwer, Kristina Casteels, Ilse Hoffman, Marijke Proesmans, Anne Rochtus

Abstract readCase Reports
In one paragraph

Article in Children (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Femke De VleeschhauwerDepartment of Pediatrics, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-9756-3533
Kristina CasteelsDepartment of Pediatrics, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-9690-3551
Ilse HoffmanDepartment of Pediatrics, University Hospitals Leuven, 3000 Leuven, Belgium.
Marijke ProesmansDepartment of Pediatrics, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-5576-9517
Anne RochtusDepartment of Pediatrics, University Hospitals Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-3266-9126

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Topical corticosteroids are a mainstay in the treatment of many pediatric disorders. While they have proven beneficial therapeutic effects and are generally considered safe, systemic adverse events may occur. This study presents four cases of children who experienced systemic adverse events after using inhaled and intranasal topical corticosteroids, as well as topical corticosteroids in other forms. A comprehensive literature review was performed to explore the existing evidence on this topic. The aim of this study is to raise awareness among healthcare providers about the possibility of systemic adverse events associated with the use of locally administered corticosteroids in pediatric patients. This information underscores the importance of careful monitoring, individualized treatment plans, and further research to better understand and mitigate the risks associated with corticosteroids, even those not given systemically.

Indexed as

adverse eventschildgrowthhypothalamic-pituitary-adrenal axisinhaled corticosteroidsintranasal corticosteroidstopical corticosteroids

Identifiers

PMID39201886
PMCPMC11353265

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.