Evidence map›Paper›PMID 39201739›Full record

ArticleInternational journal of molecular sciences2024

Serum TLR2 and TLR9 in Prostate Cancer Patients in Relation to EBV Status.

Dominika Sikora, Jacek Kiś, Ewa Stępień, Bartłomiej Drop, Małgorzata Polz-Dacewicz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dominika SikoraDepartment of Virology with Viral Diagnostics Laboratory, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0003-4031-7697
Jacek Kiś1st Clinical Military Hospital with Outpatient Clinic in Lublin, 20-049 Lublin, Poland.
Ewa StępieńDepartment of Virology with Viral Diagnostics Laboratory, Medical University of Lublin, 20-093 Lublin, Poland.
Bartłomiej DropDepartment of Medical Informatics and Statistics with e-Health Lab, Medical University of Lublin, 20-090 Lublin, Poland.
Małgorzata Polz-DacewiczDepartment of Virology with Viral Diagnostics Laboratory, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-3222-184X

Funding

Medical University of Lublin DS 233
6 · The paper itself

Abstract

The relationship between Toll-like receptors (TLRs) and prostate cancer (PCa) is complex due to the presence of the Epstein-Barr virus (EBV) infection, which has been identified as a predisposing factor for some cancers, including PCa. The present study aims to investigate these complex links by examining the levels of selected TLRs and the potential impact of EBV infection on PCa. Therefore, we examined the serum of patients with PCa. The study compared EBV(+) patients to risk groups, the Gleason score (GS), and the T-trait. Additionally, the correlation between TLR and antibody levels was examined. The results indicated that higher levels of TLR-2 and TLR-9 were observed in more advanced PCa. The findings of this study may contribute to a deeper understanding of the role of viral infections in PCa and provide information on future strategies for the diagnosis, prevention, and treatment of these malignancies.

Indexed as

Epstein-Barr Virus InfectionsHerpesvirus 4, HumanProstatic NeoplasmsToll-Like Receptor 2Toll-Like Receptor 9AgedHumansMaleMiddle AgedNeoplasm GradingTLR2 protein, humanTLR9 protein, humanToll-Like Receptor 2Toll-Like Receptor 9Epstein–Barr virusprostate cancerTLR-2TLR-9

Identifiers

PMID39201739
PMCPMC11354572

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.