Evidence map›Paper›PMID 39201649›Full record

ArticleInternational journal of molecular sciences2024

Genetic Polymorphisms in the

Anna Pierzchlińska, Jarosław Sławek, Magdalena Kwaśniak-Butowska, Damian Malinowski, Nina Komaniecka, Monika Mak, Anna Czerkawska, Arnold Kukowka, Monika Białecka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Sex differences in LDL-C genetic architecture and statin efficacy in All of Us.medRxiv : the preprint server for health sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna PierzchlińskaDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0002-1606-7918
Jarosław SławekDepartment of Neurological-Psychiatric Nursing, Faculty of Health Sciences, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Magdalena Kwaśniak-ButowskaDepartment of Neurological-Psychiatric Nursing, Faculty of Health Sciences, Medical University of Gdańsk, 80-211 Gdańsk, Poland.
Damian MalinowskiDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-8393-9627
Nina KomanieckaDepartment of Experimental and Clinical Pharmacology, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0009-0006-3162-4870
Monika MakDepartment of Health Psychology, Pomeranian Medical University, 70-111 Szczecin, Poland.
Anna CzerkawskaDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, 70-111 Szczecin, Poland.
Arnold KukowkaDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, 70-111 Szczecin, Poland.ORCID 0000-0001-5374-7827
Monika BiałeckaDepartment of Pharmacokinetics and Therapeutic Drug Monitoring, Pomeranian Medical University, 70-111 Szczecin, Poland.

Funding

Pomeranian Medical University institutional grant
6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disease characterized by motor and non-motor symptoms including cognitive impairment and dementia. The etiopathogenesis of PD, as well as its protective and susceptibility factors, are still elusive. 3-Hydroxy-3-methyglutaryl coenzyme A reductase (HMGCR) is an enzyme regulating cholesterol synthesis. Single-nucleotide polymorphisms (SNPs) in the gene coding

Indexed as

Cognitive DysfunctionGenetic Predisposition to DiseaseHydroxymethylglutaryl CoA ReductasesParkinson DiseasePolymorphism, Single NucleotideAgedCase-Control StudiesFemaleGenetic Association StudiesGenotypeHaplotypesHumansMaleMiddle AgedHMGCR protein, humanHydroxymethylglutaryl CoA Reductasescognitive declinedementiagenetic polymorphismsHMGCRlipidsParkinson’s disease

Identifiers

PMID39201649
PMCPMC11354436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.