Evidence map›Paper›PMID 39201630›Full record

ArticleInternational journal of molecular sciences2024

The Impact of Sciatic Nerve Injury on Extracellular Matrix of Lower Limb Muscle and Thoracolumbar Fascia: An Observational Study.

Xiaoxiao Zhao, Caterina Fede, Lucia Petrelli, Carmelo Pirri, Elena Stocco, Chenglei Fan, Andrea Porzionato, Cesare Tiengo, Raffaele De Caro, Stefano Masiero and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaoxiao ZhaoInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.ORCID 0009-0000-1237-3689
Caterina FedeInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-4372-7889
Lucia PetrelliInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.
Carmelo PirriInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-0119-6549
Elena StoccoInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.
Chenglei FanInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.
Andrea PorzionatoInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.
Cesare TiengoPlastic and Reconstructive Surgery Unit, Department of Neuroscience, University of Padova, 35128 Padova, Italy.ORCID 0000-0002-7493-563X
Raffaele De CaroInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-2307-0277
Stefano MasieroNeurorehabilitation Unit, Department of Neuroscience, General Hospital-University of Padova, 35121 Padova, Italy.ORCID 0000-0002-0361-4898
Carla SteccoInstitute of Human Anatomy, Department of Neurosciences, University of Padova, 35121 Padova, Italy.ORCID 0000-0002-8767-4555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve injury (PNI) is a complex clinical challenge resulting in functional disability. Neurological recovery does not always ensure functional recovery, as extracellular matrix (ECM) alterations affect muscle function. This study evaluates hyaluronan (HA) and collagen concentration in the gastrocnemius muscle and thoracolumbar fascia (TLF) in unilateral lower limb PNI rats to explore systemic ECM alterations following PNI and their impacts on functional recovery. Eighteen 8-week-old male Sprague-Dawley rats were divided into experimental (

Indexed as

CollagenExtracellular MatrixFasciaHyaluronic AcidLower ExtremityMuscle, SkeletalRats, Sprague-DawleySciatic NerveAnimalsMalePeripheral Nerve InjuriesRatsCollagenHyaluronic Acidcollagenextracellular matrixhyaluronanintramuscular connective tissueperipheral nerve injurythoracolumbar fascia

Identifiers

PMID39201630
PMCPMC11354760

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.