Evidence map›Paper›PMID 39201571›Full record

ReviewInternational journal of molecular sciences2024

Balanced Duality: H

Amira Zaher, Michael S Petronek, Bryan G Allen, Kranti A Mapuskar

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Crosslink Between Neuroinflammation and Oxidative/Nitrosative Status in the Glioblastoma Tumor Microenvironment: Prognostic and Theranostic Impact.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. MOMASTAntioxidants (Basel, Switzerland) · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amira ZaherDepartment of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-7030-0576
Michael S PetronekDepartment of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.
Bryan G AllenDepartment of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.
Kranti A MapuskarDepartment of Radiation Oncology, The University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-7311-7184

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Jon C.D. Houtman · 2000 to 2026
$70.0M
Project 3: MRI Imaging of Redox Active Fe Predicts GBM Responses to Pharmacological AscorbateP01CA217797 · NCI · UNIVERSITY OF IOWA · PI BUATTI, JOHN M · 2018 to 2022
$9.6M
Redox manipulation of iron to improve glioblastoma therapy: A phase 1 trialR21CA270742 · NCI · UNIVERSITY OF IOWA · PI ALLEN, BRYAN, BUATTI, JOHN M · 2023 to 2024
$391k
Carver College of Medicine NAHolden Comprehensive Cancer Center NANCI NIH HHS P01 CA217797NCI NIH HHS P30 CA086862NCI NIH HHS R21 CA270742NIH HHS P01 CA217797NIH HHS P30 CA086862NIH HHS R21CA270742Radiation Research Foundation L998500-G
6 · The paper itself

Abstract

Conventional cancer therapy strategies, although centered around killing tumor cells, often lead to severe side effects on surrounding normal tissues, thus compromising the chronic quality of life in cancer survivors. Hydrogen peroxide (H

Indexed as

Hydrogen PeroxideNeoplasmsAnimalsAscorbic AcidHumansOxidative StressReactive Oxygen SpeciesSuperoxide DismutaseTumor MicroenvironmentAscorbic AcidHydrogen PeroxideReactive Oxygen SpeciesSuperoxide Dismutaseantioxidantcancer therapychemotherapychemotoxicityH2O2hydrogen peroxideimmunityimmunotherapyinflammationnormal tissue injurypharmacological ascorbateprooxidantradiationradiation injuryROSsignalingsuperoxide dismutase mimetics

Identifiers

PMID39201571
PMCPMC11354297

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.