Evidence map›Paper›PMID 39201533›Full record

ArticleInternational journal of molecular sciences2024

Genome Mining and Genetic Manipulation Reveal New Isofuranonaphthoquinones in

Purna Bahadur Poudel, Dipesh Dhakal, Rubin Thapa Magar, Niranjan Parajuli, Jae Kyung Sohng

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. The genus Nocardia as a source of new antimicrobials.npj antimicrobials and resistance · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Purna Bahadur PoudelDepartment of Life Science and Biochemical Engineering, Institute of Biomolecule Reconstruction (iBR), Sun Moon University, Asan 31460, Republic of Korea.ORCID 0000-0002-3318-6900
Dipesh DhakalDepartment of Life Science and Biochemical Engineering, Institute of Biomolecule Reconstruction (iBR), Sun Moon University, Asan 31460, Republic of Korea.ORCID 0000-0002-2492-8263
Rubin Thapa MagarDepartment of Life Science and Biochemical Engineering, Institute of Biomolecule Reconstruction (iBR), Sun Moon University, Asan 31460, Republic of Korea.ORCID 0000-0001-5514-9134
Niranjan ParajuliDepartment of Life Science and Biochemical Engineering, Institute of Biomolecule Reconstruction (iBR), Sun Moon University, Asan 31460, Republic of Korea.ORCID 0000-0002-9233-6489
Jae Kyung SohngDepartment of Life Science and Biochemical Engineering, Institute of Biomolecule Reconstruction (iBR), Sun Moon University, Asan 31460, Republic of Korea.ORCID 0000-0003-1583-5046

Funding

National Research Foundation (NRF) of Korea RS-2023-00259697
6 · The paper itself

Abstract

The identification of specialized metabolites isolated from microorganisms is urgently needed to determine their roles in treating cancer and controlling multidrug-resistant pathogens. Naphthoquinones act as anticancer agents in various types of cancers, but some toxicity indicators have been limited in their appropriate application. In this context, new isofuranonaphthoquinones (ifnq) that are less toxic to humans could be promising lead compounds for developing anticancer drugs. The aim of this study is to identify and characterize novel furanonaphthoquinones (fnqs) from

Indexed as

Genome, BacterialMultigene FamilyNaphthoquinonesNocardiaAnti-Bacterial AgentsAntineoplastic AgentsBacterial ProteinsHumansAnti-Bacterial AgentsAntineoplastic AgentsBacterial ProteinsNaphthoquinonesanticancerantimicrobialCRISPR-Cas9SARP regulatorsecondary metabolites

Identifiers

PMID39201533
PMCPMC11354674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.