Evidence map›Paper›PMID 39201481›Full record

ArticleInternational journal of molecular sciences2024

Regulation of TIR-1/SARM-1 by miR-71 Protects Dopaminergic Neurons in a

Devin Naidoo, Alexandre de Lencastre

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Unraveling Molecular Targets for Neurodegenerative Diseases ThroughInternational journal of molecular sciences · 2025
    Review
  3. Studying the mechanisms of neurodegeneration:Frontiers in cellular neuroscience · 2025
    Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Devin NaidooFrank H. Netter MD School of Medicine, Quinnipiac University, North Haven, CT 06473, USA.ORCID 0000-0003-1941-4935
Alexandre de LencastreDepartment of Biological Sciences, Quinnipiac University, Hamden, CT 06518, USA.ORCID 0000-0002-3951-8515

Funding

Quinnipiac University N/A
6 · The paper itself

Abstract

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by symptoms such as bradykinesia, resting tremor, and rigidity, primarily driven by the degradation of dopaminergic (DA) neurons in the substantia nigra. A significant contributor to familial autosomal dominant PD cases is mutations in the LRRK2 gene, making it a primary therapeutic target. This study explores the role of microRNAs (miRNAs) in regulating the proteomic stress responses associated with neurodegeneration in PD using

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsDisease Models, AnimalDopaminergic NeuronsLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MicroRNAsParkinson DiseaseAnimalsHumansMutationCaenorhabditis elegans ProteinsLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MicroRNAsagingelegansmiRNAneurodegenerationParkinson

Identifiers

PMID39201481
PMCPMC11354575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.