Evidence map›Paper›PMID 39201428›Full record

ArticleInternational journal of molecular sciences2024

ABCC1 Is a ΔNp63 Target Gene Overexpressed in Squamous Cell Carcinoma.

Veronica La Banca, Sara De Domenico, Sara Nicolai, Veronica Gatti, Stefano Scalera, Marcello Maugeri, Alessandro Mauriello, Manuela Montanaro, Jens Pahnke, Eleonora Candi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Veronica La BancaDepartment of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0003-0206-8394
Sara De DomenicoDepartment of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.
Sara NicolaiInstitute of Translational Pharmacology (IFT), CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy.
Veronica GattiInstitute of Translational Pharmacology (IFT), CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0002-4233-7379
Stefano ScaleraUOSD Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.ORCID 0000-0001-5192-5917
Marcello MaugeriUOSD Clinical Trial Center, Biostatistics and Bioinformatics Division, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy.
Alessandro MaurielloDepartment of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0002-7351-5676
Manuela MontanaroDepartment of Biomedicine and Prevention, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.ORCID 0000-0001-8441-3731
Jens PahnkeTranslational Neurodegeneration Research and Neuropathology Lab/Section of Neuropathology Research, Department of Pathology (PAT), Medical Faculty/Clinical Medicine (KlinMed), Clinics for Laboratory Medicine (KLM), University of Oslo (UiO) and Oslo University Hospital (OUS), Sognsvannsveien 20, 0372 Oslo, Norway.ORCID 0000-0001-7355-4213
Eleonora CandiDepartment of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.
Silvia D'AmicoInstitute of Translational Pharmacology (IFT), CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0002-9805-4589
Angelo PeschiaroliInstitute of Translational Pharmacology (IFT), CNR, Via Fosso del Cavaliere 100, 00133 Rome, Italy.

Funding

Associazione Italiana per la Ricerca sul Cancro IG#24678Progetto di ricerca di Rilevante Interesse Nazionale (PRIN) 2022WW4J4BProgetto di ricerca di Rilevante Interesse Nazionale (PRIN) nell'ambito del PNRR (PRIN_PNRR_2022) P2022HLKRZ
6 · The paper itself

Abstract

The transcription factor ΔNp63 plays a pivotal role in maintaining the integrity of stratified epithelial tissues by regulating the expression of distinct target genes involved in lineage specification, cell stemness, cell proliferation and differentiation. Here, we identified the ABC transporter subfamily member

Indexed as

ATP-Binding Cassette, Sub-Family C ProteinsCarcinoma, Squamous CellCell ProliferationGene Expression Regulation, NeoplasticKeratinocytesSkin NeoplasmsTranscription FactorsTumor Suppressor ProteinsAnimalsCell DifferentiationCell Line, TumorHumansMiceMice, KnockoutTrans-ActivatorsATP-Binding Cassette, Sub-Family C Proteinsmultidrug resistance-associated protein 1TP63 protein, humanTrans-ActivatorsTranscription FactorsTumor Suppressor ProteinsABC transporterepidermal differentiationp63skin inflammation

Identifiers

PMID39201428
PMCPMC11354449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.