Evidence map›Paper›PMID 39201283›Full record

ArticleInternational journal of molecular sciences2024

Physical Activity and Epigenetic Aging in Breast Cancer Treatment.

Chantalle Moulton, Elisa Grazioli, José Santiago Ibáñez-Cabellos, Arianna Murri, Claudia Cerulli, Monica Silvestri, Daniela Caporossi, Federico V Pallardó, José Luis García-Giménez, Stefano Magno and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Special Issue "Skeletal Muscle Adaptations to Oxidative Stress".International journal of molecular sciences · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chantalle MoultonUnit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0009-0002-8865-8562
Elisa GrazioliUnit of Physical Exercise and Sport Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0003-4245-1320
José Santiago Ibáñez-CabellosEpiDisease S.L., Scientific Park, University of Valencia, 46026 Paterna, Spain.ORCID 0000-0002-2462-653X
Arianna MurriUnit of Physical Exercise and Sport Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0003-4642-6317
Claudia CerulliUnit of Physical Exercise and Sport Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0003-2637-7968
Monica SilvestriUnit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.
Daniela CaporossiUnit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0001-9628-0665
Federico V PallardóDepartment of Physiology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-3715-1980
José Luis García-GiménezDepartment of Physiology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-7547-7872
Stefano MagnoCenter for Integrative Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00136 Rome, Italy.ORCID 0000-0002-3721-9693
Cristina RossiCenter for Integrative Oncology, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00136 Rome, Italy.ORCID 0000-0001-5157-6681
Guglielmo DurantiUnit of Biochemistry and Molecular Biology, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0002-1664-9387
Salvador Mena-MollaEpiDisease S.L., Scientific Park, University of Valencia, 46026 Paterna, Spain.
Attilio ParisiUnit of Physical Exercise and Sport Sciences, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0003-2648-8406
Ivan DimauroUnit of Biology and Genetics of Movement, Department of Movement, Human and Health Sciences, University of Rome Foro Italico, 00135 Rome, Italy.ORCID 0000-0003-0577-3144

Funding

CREATEC-CV grant cofounding by IVACE (Valencian region) and FEDER (European Union) IMCBTA/2018/29MUR Italy PNR 2021-2027, DM n. 737 del 25-06-2021
6 · The paper itself

Abstract

Biological age, reflecting the cumulative damage in the body over a lifespan, is a dynamic measure more indicative of individual health than chronological age. Accelerated aging, when biological age surpasses chronological age, is implicated in poorer clinical outcomes, especially for breast cancer (BC) survivors undergoing treatments. This preliminary study investigates the impact of a 16-week online supervised physical activity (PA) intervention on biological age in post-surgery female BC patients. Telomere length was measured using qPCR, and the ELOVL2-based epigenetic clock was assessed via DNA methylation pyrosequencing of the

Indexed as

AgingBreast NeoplasmsDNA MethylationEpigenesis, GeneticExerciseFatty Acid ElongasesAdultAgedFemaleHumansMiddle AgedPromoter Regions, GeneticTelomereELOVL2 protein, humanFatty Acid ElongasesDNA methylationepigenetic clockexercisetelomere

Identifiers

PMID39201283
PMCPMC11355047

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.