Evidence map›Paper›PMID 39201260›Full record

ArticleInternational journal of molecular sciences2024

Immunomodulatory Effects of a Probiotic Mixture: Alleviating Colitis in a Mouse Model through Modulation of Cell Activation Markers and the Gut Microbiota.

Hye-Myung Ryu, S M Shamsul Islam, Bushra Riaz, Hasan M Sayeed, Bunsoon Choi, Seonghyang Sohn

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hye-Myung RyuDepartment of Microbiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.ORCID 0000-0003-0349-9815
S M Shamsul IslamDepartment of Biomedical Sciences, Ajou University School of Medicine, Suwon 16499, Republic of Korea.ORCID 0000-0003-0617-1698
Bushra RiazDepartment of Biomedical Sciences, Ajou University School of Medicine, Suwon 16499, Republic of Korea.ORCID 0000-0001-5754-1324
Hasan M SayeedDepartment of Biomedical Sciences, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Bunsoon ChoiInstitute of Medical Science, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Seonghyang SohnDepartment of Microbiology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a persistent inflammatory intestinal disease that consistently affects the colon and rectum. Its exact cause remains unknown. UC causes a considerable challenge in healthcare, prompting research for novel therapeutic strategies. Although probiotics have gained popularity as possible candidates for managing UC, studies are still ongoing to identify the best probiotics or probiotic mixtures for clinical applications. This study aimed to determine the efficacy of a multi-strain probiotic mixture in mitigating intestinal inflammation in a colitis mouse model induced by dextran sulfate sodium. Specifically, a multi-strain probiotic mixture consisting of

Indexed as

ColitisDextran SulfateDisease Models, AnimalGastrointestinal MicrobiomeProbioticsAnimalsBiomarkersColitis, UlcerativeColonMiceMice, Inbred C57BLRNA, Ribosomal, 16SBiomarkersDextran SulfateRNA, Ribosomal, 16Scolitiscostimulatory moleculesgut microbiotainflammationmouse modelprobiotics

Identifiers

PMID39201260
PMCPMC11354276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.