Evidence map›Paper›PMID 39201246›Full record

ArticleInternational journal of molecular sciences2024

Valpalf

Luigi Rosa, Giusi Ianiro, Antonella Niro, Giovanni Musci, Rosalba Paesano, Antimo Cutone, Piera Valenti

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Special Issue "New Insights into Lactoferrin".International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luigi RosaDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-1252-6080
Giusi IaniroDepartment of Biosciences and Territory, University of Molise, 86090 Pesche, Italy.ORCID 0000-0002-3033-8120
Antonella NiroDepartment of Biosciences and Territory, University of Molise, 86090 Pesche, Italy.
Giovanni MusciDepartment of Biosciences and Territory, University of Molise, 86090 Pesche, Italy.ORCID 0000-0002-5196-709X
Rosalba PaesanoMicrobo s.r.l., 00153 Rome, Italy.
Antimo CutoneDepartment of Biosciences and Territory, University of Molise, 86090 Pesche, Italy.ORCID 0000-0002-7492-8616
Piera ValentiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a nutraceutical, bovine lactoferrin (bLf), an iron-binding glycoprotein involved in innate immunity, is gaining elevated attention for its ability to exert pleiotropic functions and to be exceptionally tolerated even at high dosages. Some of bLf's activities, including its anti-inflammatory and antioxidant, are tightly linked to its ability to both chelate iron and enter inside the cell nucleus. Here, we present data about Valpalf

Indexed as

Dietary SupplementsInterleukin-6LactoferrinSuperoxide DismutaseAnemiaAnimalsAnti-Inflammatory AgentsAntioxidantsCattleFemaleHumansIronLipopolysaccharidesMacrophagesMiceMonocytesAnti-Inflammatory AgentsAntioxidantsInterleukin-6IronLactoferrinLipopolysaccharidesSodium BicarbonateSodium CitrateSuperoxide DismutaseSuperoxide Dismutase-1Superoxide Dismutase 2anemia of inflammationanti-inflammatory activityantioxidant activitybovine lactoferriniron chelationproteolysis resistanceValpalf®

Identifiers

PMID39201246
PMCPMC11354537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.