Evidence map›Paper›PMID 39201194›Full record

ReviewHealthcare (Basel, Switzerland)2024

Lower-Limb Exoskeletons for Gait Training in Parkinson's Disease: The State of the Art and Future Perspectives.

Matteo Fortunati, Massimiliano Febbi, Massimo Negro, Federico Gennaro, Giuseppe D'Antona, Oscar Crisafulli

Abstract readReview
In one paragraph

Review in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Gait analysis for Parkinson's disease using multiscale entropy.Neurodegenerative disease management · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matteo FortunatiDepartment of Industrial Engineering, University of Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-5738-2298
Massimiliano FebbiDepartment of Industrial Engineering, University of Tor Vergata, 00133 Rome, Italy.ORCID 0000-0003-1091-997X
Massimo NegroCRIAMS-Sport Medicine Centre Voghera, University of Pavia, 27058 Voghera, Italy.ORCID 0000-0002-9159-9287
Federico GennaroDepartment of Biomedical Sciences, University of Padua, 35131 Padua, Italy.ORCID 0000-0003-2203-2858
Giuseppe D'AntonaCRIAMS-Sport Medicine Centre Voghera, University of Pavia, 27058 Voghera, Italy.ORCID 0000-0002-0683-5565
Oscar CrisafulliCRIAMS-Sport Medicine Centre Voghera, University of Pavia, 27058 Voghera, Italy.ORCID 0000-0002-8586-6465

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gait dysfunction (GD) is a common impairment of Parkinson's disease (PD), which negatively impacts patients' quality of life. Among the most recent rehabilitation technologies, a lower-limb powered exoskeleton (LLEXO) arises as a useful instrument for gait training in several neurological conditions, including PD. However, some questions relating to methods of use, achievable results, and usefulness compared to traditional rehabilitation methodologies still require clear answers. Therefore, in this review, we aim to summarise and analyse all the studies that have applied an LLEXO to train gait in PD patients. Literature research on PubMed and Scopus retrieved five articles, comprising 46 PD participants stable on medications (age: 71.7 ± 3.7 years, 24 males, Hoehn and Yahr: 2.1 ± 0.6). Compared to traditional rehabilitation, low-profile lower-limb exoskeleton (lp-LLEXO) training brought major improvements towards walking capacity and gait speed, while there are no clear major benefits regarding the dual-task gait cost index and freezing of gait symptoms. Importantly, the results suggest that lp-LLEXO training is more beneficial for patients with an intermediate-to-severe level of disease severity (Hoehn and Yahr > 2.5). This review could provide a novel framework for implementing LLEXO in clinical practise, highlighting its benefits and limitations towards gait training.

Indexed as

disease severitydual-task gaitgait functiongait traininglow-profile lower-limb exoskeletonParkinson’s diseaserobot-assisted gait training

Identifiers

PMID39201194
PMCPMC11353983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.