Evidence map›Paper›PMID 39200922›Full record

ReviewJournal of clinical medicine2024

Global Insights on Prehospital Stroke Care: A Comprehensive Review of Challenges and Solutions in Low- and Middle-Income Countries.

Elvan Wiyarta, Marc Fisher, Mohammad Kurniawan, Rakhmad Hidayat, Iskandar Purba Geraldi, Qaisar Ali Khan, I Putu Eka Widyadharma, Aliena Badshah, Jeyaraj Durai Pandian

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Targeting Neurovascular Pathways: Gene Therapy as a Novel Treatment for Vascular Dementia After Stroke.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Prehospital stroke care in low- and middle-income countries: A World Stroke Organization (WSO) scientific statement.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
  13. Time delays in emergency stroke care in a low-resource referral hospital in Ghana.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  14. Article
  15. Delays in the Stroke Care Pathway in a Low-Income Setting: An Audit Study from Mozambique.International journal of environmental research and public health · 2025
    Observational
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elvan WiyartaDepartment of Neurology, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Jakarta 10430, Indonesia.ORCID 0000-0002-5676-7804
Marc FisherBeth Israel Deaconess Medical Center, Boston, MA 02215, USA.
Mohammad KurniawanDepartment of Neurology, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Jakarta 10430, Indonesia.
Rakhmad HidayatDepartment of Neurology, Faculty of Medicine, Universitas Indonesia-Dr. Cipto Mangunkusumo National Hospital, Central Jakarta, Jakarta 10430, Indonesia.ORCID 0000-0003-4615-5246
Iskandar Purba GeraldiCengkareng General Hospital, West Jakarta, Jakarta 11730, Indonesia.ORCID 0009-0000-7150-0836
Qaisar Ali KhanDepartment of Medicine, Khyber Teaching Hospital, Peshawar 25120, Pakistan.
I Putu Eka WidyadharmaDepartment of Neurology, Faculty of Medicine, Universitas Udayana, Bali 80361, Indonesia.ORCID 0000-0002-4554-0348
Aliena BadshahDepartment of Medicine, Khyber Teaching Hospital, Peshawar 25120, Pakistan.
Jeyaraj Durai PandianChristian Medical College, Ludhiana 141008, Punjab, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is a leading cause of disability and mortality worldwide, and it disproportionately affects low- and middle-income countries (LMICs), which account for 88% of stroke fatalities. Prehospital stroke care delays are a crucial obstacle to successful treatment in these settings, especially given the limited therapeutic window for thrombolytic treatments, which may greatly improve recovery chances when initiated early after stroke onset. These delays are caused by a lack of public understanding of stroke symptoms, sociodemographic and cultural variables, and insufficient healthcare infrastructure. This review discusses these issues in detail, emphasizing the disparities in stroke awareness and reaction times between locations and socioeconomic classes. Innovative options for reducing these delays include the deployment of mobile stroke units and community-based educational campaigns. This review also discusses how technology improvements and personalized educational initiatives might improve stroke awareness and response in LMICs. The primary goal is to give a thorough assessment of the challenges and potential remedies that might serve as the foundation for policy reforms and healthcare improvements in LMICs, eventually improving stroke care and lowering disease-related mortality and disability.

Indexed as

emergency medical serviceshealthcare infrastructurelow- and middle-income countriesmobile stroke unitsprehospital stroke carepublic health educationstroke awarenessstroke managementtelemedicinethrombolytic therapy

Identifiers

PMID39200922
PMCPMC11355367

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.