Evidence map›Paper›PMID 39200312›Full record

ReviewBiomedicines2024

Quantification of Ions in Human Urine-A Review for Clinical Laboratories.

Ana Rita Ferrão, Paula Pestana, Lígia Borges, Rita Palmeira-de-Oliveira, Ana Palmeira-de-Oliveira, José Martinez-de-Oliveira

Abstract readReview
In one paragraph

Review in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Intercalated bacterial biofilms are intrinsic internal components of calcium-based kidney stones.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana Rita FerrãoCentro Hospitalar Universitário Cova da Beira, EPE, 6200 Covilhã, Portugal.ORCID 0000-0003-4897-4739
Paula PestanaCentro Hospitalar Universitário Cova da Beira, EPE, 6200 Covilhã, Portugal.
Lígia BorgesLabfit-HPRD, 6200 Covilhã, Portugal.
Rita Palmeira-de-OliveiraLabfit-HPRD, 6200 Covilhã, Portugal.ORCID 0000-0001-9311-8355
Ana Palmeira-de-OliveiraHealth Sciences Research Centre, Universidade da Beira Interior, 6201 Covilhã, Portugal.
José Martinez-de-OliveiraHealth Sciences Research Centre, Universidade da Beira Interior, 6201 Covilhã, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urine is an organic fluid produced by the kidney, and its analysis is one of the most requested laboratory tests by clinicians. The ionic composition of urine has been shown to be a good health indicator: it is useful for the diagnosis of several diseases, as well as monitoring therapeutics. This review considers laboratorial techniques that have been used throughout time for the quantification of ions in urine, and also considers some methodologies that can potentially be used in clinical laboratories for this kind of analysis. Those methods include gravimetry, titration, flame emission spectrophotometry (flame photometry), fluorimetry, potentiometry (ion selective electrodes), ion chromatography, electrophoresis, kinetic colorimetric tests, enzymatic colorimetric tests, flow cytometry, atomic absorption, plasma atomic emission spectrometry, and paper-based devices. Sodium, potassium, chloride, calcium, and magnesium are among the most important physiological ions, and their determination is frequently requested in hospitals. There have been many advances regarding the analysis of these ions in 24 h urine. However, there is still some way to go concerning the importance of intracellular ions in this type of sample as well as the use of occasional urine for monitoring these parameters.

Indexed as

clinical laboratory testsionsurine

Identifiers

PMID39200312
PMCPMC11351741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.