Evidence map›Paper›PMID 39200156›Full record

ArticleBiomedicines2024

Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse.

Zahra Shabani, Leandro Barbosa Do Prado, Rui Zhang, Wan Zhu, Sonali S Shaligram, Alka Yadav, Calvin Wang, Hua Su

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Translational relevance of animal models available on brain arteriovenous malformations, a systematic review.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zahra ShabaniCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Leandro Barbosa Do PradoCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Rui ZhangCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Wan ZhuCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Sonali S ShaligramCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Alka YadavCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Calvin WangCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.
Hua SuCenter for Cerebrovascular Research, University of California, San Francisco, CA 94143, USA.ORCID 0000-0003-1566-9877

Funding

Uncover the Pathogenesis of Brain Arteriovenous MalformationR01NS027713 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SU, HUA · 1990 to 2023
$8.6M
Reduction of Brain AVM Severity through Inhibition of Pathogenic AngiogenesisR01NS112819 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SU, HUA · 2020 to 2024
$2.9M
NIH HHS NS027713NIH HHS NS112819NINDS NIH HHS R01 NS027713NINDS NIH HHS R01 NS112819
6 · The paper itself

Abstract

Endoglin (

Indexed as

arteriovenous malformationsendoglinendothelial cellshereditary hemorrhagic telangiectasia

Identifiers

PMID39200156
PMCPMC11352040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.