Evidence map›Paper›PMID 39200023›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Investigating the Antimicrobial Potential of 560 Compounds from the Pandemic Response Box and COVID Box against Resistant Gram-Negative Bacteria.

Rita de Cássia Cerqueira Melo, Aline Andrade Martins, Andressa Leite Ferraz Melo, Jean Carlos Pael Vicente, Mariana Carvalho Sturaro, Julia Pimentel Arantes, Luana Rossato, Gleyce Hellen de Almeida de Souza, Simone Simionatto

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rita de Cássia Cerqueira MeloHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0002-4973-7965
Aline Andrade MartinsHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0001-7194-1068
Andressa Leite Ferraz MeloHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.
Jean Carlos Pael VicenteHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.
Mariana Carvalho SturaroHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0009-0003-0455-9258
Julia Pimentel ArantesHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0002-9089-4057
Luana RossatoHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0002-6115-3313
Gleyce Hellen de Almeida de SouzaHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0001-8860-9109
Simone SimionattoHealth Sciences Research Laboratory, Federal University of Grande Dourados (UFGD), Dourados 79804970, Mato Grosso do Sul, Brazil.ORCID 0000-0003-2367-0915

Funding

Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul under Grants 76/2023 and 113/2023National Council for Scientific and Technological Development Subsídios 408778/2022-9, 307946/2022-3, 420743/2023-5 e 444735/2023-2;
6 · The paper itself

Abstract

Antimicrobial resistance (AMR) has emerged as a significant threat to public health, particularly in infections caused by critically important Gram-negative bacteria. The development of novel antibiotics has its limitations, and therefore it is crucial to explore alternative strategies to effectively combat infections with resistant pathogens. In this context, the present study investigated the antibacterial potency of 560 compounds against the multidrug-resistant (MDR) strains of

Indexed as

antimicrobial resistancedrug screeningGram-negative bacteriamultidrug-resistant resistance

Identifiers

PMID39200023
PMCPMC11350835

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.