Evidence map›Paper›PMID 39200021›Full record

ArticleAntibiotics (Basel, Switzerland)2024

Impact of Manual Addition of Vancomycin to Polymethylmethacrylate (PMMA) Cements.

Clemens Kittinger, Michael Eder-Halbedl, Klaus Dieter Kühn

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Clemens KittingerDevelopment and Research Insitute of Hygiene, Microbiology and Environmental Medicine, Hygiene Medical University of Graz, Neue Stiftingtalstraße 6/III 1, 8010 Graz, Austria.ORCID 0000-0001-8472-2155
Michael Eder-HalbedlDepartment of Orthopedics and Trauma, LKH-Feldbach, Ottokar-Kernstock-Straße 18, 8330 Feldbach, Austria.ORCID 0000-0002-9295-0972
Klaus Dieter KühnDepartment of Orthopaedics and Trauma, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-6747-4943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: The addition of antibiotics to bone cements is a common practice in the treatment of periprosthetic joint infections. In revision cases, the amount and type of antibiotic is often insufficient and additional antibiotics must be added. The addition, however, changes the product itself, and the surgeon becomes the "manufacturer" of the bone cement. PMMAe wished to clarify whether the admixture of antibiotics changes the mechanical stability of the bone cements used and if the added antibiotics were still functional and released in sufficient quantities. (2) Methods: We compared two industrially manufactured vancomycin-containing PMMA cements; the low-viscous VancogenX

Indexed as

Copal G+Vefficacyelutionmanually added vancomycinmechanical propertiesPMMAVancogenX

Identifiers

PMID39200021
PMCPMC11350699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.