Evidence map›Paper›PMID 39199735›Full record

ReviewBioengineering (Basel, Switzerland)2024

Three-Dimensional Bioprinting: A Comprehensive Review for Applications in Tissue Engineering and Regenerative Medicine.

Nicholas A Mirsky, Quinn T Ehlen, Jason A Greenfield, Michael Antonietti, Blaire V Slavin, Vasudev Vivekanand Nayak, Daniel Pelaez, David T Tse, Lukasz Witek, Sylvia Daunert and 1 more

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
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  14. Review
  15. 3D Bioprinting Strategies in Autoimmune Disease Models.International journal of molecular sciences · 2025
    Review
  16. Review
  17. Bioprinting for craniofacial reconstruction: A review of advancements, clinical use, and challenges.Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery · 2025
    Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas A MirskyUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Quinn T EhlenUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Jason A GreenfieldUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Michael AntoniettiUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Blaire V SlavinUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Vasudev Vivekanand NayakDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-2739-0339
Daniel PelaezDr. Nasser Ibrahim Al-Rashid Orbital Vision Research Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-4483-5160
David T TseDr. Nasser Ibrahim Al-Rashid Orbital Vision Research Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Lukasz WitekBiomaterials Division, NYU Dentistry, New York, NY 10010, USA.ORCID 0000-0003-1458-6527
Sylvia DaunertDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Paulo G CoelhoDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Funding

Purinergic Stimulation of Bone RegenerationR01AR068593 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COELHO, PAULO G, CRONSTEIN, BRUCE NEIL · 2015 to 2019
$2.8M
Engineering Personalized Devices for Craniomaxillofacial DefectsR33HD090664 · NICHD · NEW YORK UNIVERSITY · PI CRONSTEIN, BRUCE NEIL, FLORES, ROBERTO L · 2019 to 2021
$1.2M
Engineering Personalized Devices for Craniomaxillofacial DefectsR21HD090664 · NICHD · NEW YORK UNIVERSITY · PI COELHO, PAULO G, CRONSTEIN, BRUCE NEIL · 2017 to 2018
$452k
NIAMS NIH HHS R01 AR068593NICHD NIH HHS R21 HD090664NICHD NIH HHS R33 HD090664NIH-NIAMS R01AR068593NIH-NICHD R21HD090664NIH-NICHD R33HD090664
6 · The paper itself

Abstract

Since three-dimensional (3D) bioprinting has emerged, it has continuously to evolved as a revolutionary technology in surgery, offering new paradigms for reconstructive and regenerative medical applications. This review highlights the integration of 3D printing, specifically bioprinting, across several surgical disciplines over the last five years. The methods employed encompass a review of recent literature focusing on innovations and applications of 3D-bioprinted tissues and/or organs. The findings reveal significant advances in the creation of complex, customized, multi-tissue constructs that mimic natural tissue characteristics, which are crucial for surgical interventions and patient-specific treatments. Despite the technological advances, the paper introduces and discusses several challenges that remain, such as the vascularization of bioprinted tissues, integration with the host tissue, and the long-term viability of bioprinted organs. The review concludes that while 3D bioprinting holds substantial promise for transforming surgical practices and enhancing patient outcomes, ongoing research, development, and a clear regulatory framework are essential to fully realize potential future clinical applications.

Indexed as

3D bioprintingbioinksophthalmologyorthopedic surgeryplastic and reconstructive surgeryregenerative medicinesurgical implantstissue engineering

Identifiers

PMID39199735
PMCPMC11351251

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.