Evidence map›Paper›PMID 39199656›Full record

ArticleCancers2024

Perioperative Predictive Factors for Tumor Regression and Survival in Non-Small Cell Lung Cancer Patients Undergoing Neoadjuvant Treatment and Lung Resection.

Fuad Damirov, Mircea Gabriel Stoleriu, Farkhad Manapov, Enole Boedeker, Sascha Dreher, Sibylle Gerz, Thomas Hehr, Evelin Sandner, German Ott, Rudolf Alexander Hatz and 1 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fuad DamirovDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU) and Asklepios Lung Clinic, Munich-Gauting, 82131 Gauting, Germany.ORCID 0000-0001-6982-2369
Mircea Gabriel StoleriuDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU) and Asklepios Lung Clinic, Munich-Gauting, 82131 Gauting, Germany.
Farkhad ManapovInstitute for Lung Health and Immunity, Comprehensive Pneumology Center with the CPC-M BioArchive, Helmholtz Center Munich, Member of the German Lung Research Center (DZL), 81377 Munich, Germany.
Enole BoedekerDepartment of Thoracic Surgery, RBK-Lungenzentrum Stuttgart, Schillerhöhe Lung Clinic, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Sascha DreherDepartment of Thoracic Surgery, RBK-Lungenzentrum Stuttgart, Schillerhöhe Lung Clinic, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Sibylle GerzDepartment of Thoracic Surgery, RBK-Lungenzentrum Stuttgart, Schillerhöhe Lung Clinic, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Thomas HehrDepartment of Radiation Oncology, Marienhospital Stuttgart, 70199 Stuttgart, Germany.
Evelin SandnerDepartment of Oncology, Robert Bosch Hospital, 70376 Stuttgart, Germany.
German OttDepartment of Clinical Pathology, Robert Bosch Hospital, 70376 Stuttgart, Germany.
Rudolf Alexander HatzDepartment of Thoracic Surgery, Ludwig Maximilian University of Munich (LMU) and Asklepios Lung Clinic, Munich-Gauting, 82131 Gauting, Germany.
Gerhard PreisslerDepartment of Thoracic Surgery, RBK-Lungenzentrum Stuttgart, Schillerhöhe Lung Clinic, Robert Bosch Hospital, 70376 Stuttgart, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aimed to identify predictors for the effectiveness of tumor regression in lung cancer patients undergoing neoadjuvant treatment and cancer resections. Patients admitted between 2016 and 2022 were included in the study. Based on the histology of the tumor, patients were categorized into a lung adenocarcinoma group (LUAD) and squamous cell carcinoma group (SQCA). Ninety-five patients with non-small-cell lung cancer were included in the study. A total of 58 (61.1%) and 37 (38.9%) patients were included in the LUAD and SQCA groups, respectively. Additionally, 9 (9.5%), 56 (58.9%), and 30 (31.6%) patients were categorized with a tumor regression score of I, II, and III, respectively. In multivariable analyses, histology of the primary tumor (SQCA), lymph node size in the preoperative CT scan (>1.7 cm), and absolute tumor size reduction after neoadjuvant treatment (>2.6 cm) independently predict effectiveness of tumor regression (OR [95% confidence interval, p-value] of 6.88 [2.40-19.77,

Indexed as

lung cancerlymph node stagingneoadjuvant therapyoverall survivalpathological responsePET/CT-scantumor regression

Identifiers

PMID39199656
PMCPMC11352403

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.