Evidence map›Paper›PMID 39199581›Full record

ArticleCancers2024

Conventional Spinal Chordomas: Investigation of SMARCB1/INI1 Protein Expression, Genetic Alterations in

Margherita Maioli, Stefania Cocchi, Marco Gambarotti, Stefania Benini, Giovanna Magagnoli, Gabriella Gamberi, Cristiana Griffoni, Alessandro Gasbarrini, Riccardo Ghermandi, Luigi Emanuele Noli and 6 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Margherita MaioliDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-2969-6019
Stefania CocchiDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0001-6853-4621
Marco GambarottiDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-8080-4484
Stefania BeniniDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Giovanna MagagnoliDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-6430-1318
Gabriella GamberiDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Cristiana GriffoniDepartment of Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0001-8344-7534
Alessandro GasbarriniDepartment of Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Riccardo GhermandiDepartment of Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Luigi Emanuele NoliDepartment of Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Chiara AlcherigiDepartment of Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Cristina FerrariExperimental Oncology Laboratory, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-7755-5085
Giuseppe BianchiDepartment of Orthopedic Oncology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0001-6390-9762
Sofia AsioliDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-5035-2448
Elettra PignottiDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Alberto RighiDepartment of Pathology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-1074-0155

Funding

Fondazione CARISBO Project #19344
6 · The paper itself

Abstract

The partial loss of SMARCB1/INI1 expression has recently been reported in skull base conventional chordomas, with possible therapeutic implications. We retrospectively analyzed 89 patients with conventional spinal chordomas to investigate the differences in the immunohistochemical expression of SMARCB1/INI1 and the underlying genetic alterations in the

Indexed as

conventional chordomaFISH analysisSMARCB1 geneSMARCB1/INI1

Identifiers

PMID39199581
PMCPMC11353163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.