Evidence map›Paper›PMID 39199476›Full record

ArticleBrain sciences2024

Abnormal Dynamic Reconstruction of Overlapping Communities in Schizophrenia Patients.

Yuxiang Guo, Xubin Wu, Yumeng Sun, Yanqing Dong, Jie Sun, Zize Song, Jie Xiang, Xiaohong Cui

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In one paragraph

Article in Brain sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yuxiang GuoSchool of Software, Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Xubin WuCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Yumeng SunCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Yanqing DongCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Jie SunCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Zize SongCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.
Jie XiangCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.ORCID 0000-0002-9758-6954
Xiaohong CuiCollege of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, No.209, University Street, Jinzhong 030600, China.

Funding

National Natural Science Foundation of China 62376184, 62303445, 62206196, 62176177
6 · The paper itself

Abstract

objectiveThis study aims to explore the changes in dynamic overlapping communities in the brains of schizophrenia (SZ) patients and further investigate the dynamic restructuring patterns of overlapping communities in SZ patients. MATERIALS AND

methodsA total of 43 SZ patients and 49 normal controls (NC) were selected for resting-state functional MRI (rs-fMRI) scans. Dynamic functional connectivity analysis was conducted separately on SZ patients and NC using rs-fMRI and Jackknife Correlation techniques to construct dynamic brain network models. Based on these models, a dynamic overlapping community detection method was utilized to explore the abnormal overlapping community structure in SZ patients using evaluation metrics such as the structural stability of overlapping communities, nodes' functional diversity, and activity level of overlapping communities.

resultsThe stability of communities in SZ patients showed a decreasing trend. The changes in the overlapping community structure of SZ patients may be related to a decrease in the diversity of overlapping node functions. Additionally, compared to the NC group, the activity level of overlapping communities of SZ patients was significantly reduced.

conclusionThe structure or organization of the brain functional network in SZ patients is abnormal or disrupted, and the activity of the brain network in information processing and transmission is weakened in SZ patients.

Indexed as

community restructuringdynamic brain networkdynamic overlapping community algorithmfMRIschizophrenia

Identifiers

PMID39199476
PMCPMC11352520

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.