Evidence map›Paper›PMID 39199341›Full record

ArticleBiomolecules2024

Burst-Suppression EEG Reactivity to Photic Stimulation-A Translational Biomarker in Hypoxic-Ischemic Brain Injury.

Alexandru-Cătălin Pâslaru, Alexandru Călin, Vlad-Petru Morozan, Mihai Stancu, Laurențiu Tofan, Anca Maria Panaitescu, Ana-Maria Zăgrean, Leon Zăgrean, Mihai Moldovan

Abstract read
In one paragraph

Article in Biomolecules, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandru-Cătălin PâslaruDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-9054-3257
Alexandru CălinDepartment of Clinical Neurophysiology, King's College Hospital NHS Foundation Trust, London SE59RS, UK.ORCID 0000-0003-2363-2898
Vlad-Petru MorozanDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mihai StancuDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Laurențiu TofanDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Anca Maria PanaitescuDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-9213-6735
Ana-Maria ZăgreanDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0002-4302-629X
Leon ZăgreanDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Mihai MoldovanDivision of Physiology-Neuroscience, Department of Functional Sciences, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-2512-3499

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-II-ID-PCE-2011-3-0847, PN-II-PT-PCCA-2011-3.2-1290 and PN-III-P2-2.1-PTE-2016-0114
6 · The paper itself

Abstract

The reactivity of an electroencephalogram (EEG) to external stimuli is impaired in comatose patients showing burst-suppression (BS) patterns following hypoxic-ischemic brain injury (HIBI). We explored the reactivity of BS induced by isoflurane in rat models of HIBI and controls using intermittent photic stimulation (IPS) delivered to one eye. The relative time spent in suppression referred to as the suppression ratio (SR) was measured on the contralateral fronto-occipital cortical EEG channel. The BS reactivity (BSR) was defined as the decrease in the SR during IPS from the baseline before stimulation (SR

Indexed as

BiomarkersElectroencephalographyHypoxia-Ischemia, BrainPhotic StimulationAnimalsDisease Models, AnimalFemaleHumansIsofluraneMaleOxytocinRatsRats, Sprague-DawleyBiomarkersIsofluraneOxytocinclinical neurophysiologycomaglobal cerebral ischemiaperinatal asphyxiarat

Identifiers

PMID39199341
PMCPMC11352952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.