ArticleAntioxidants (Basel, Switzerland)2024
A Structure-Activity Relationship Study on the Antioxidant Properties of Dithiocarbamic Flavanones.
Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Towards the Development of Effective Antioxidants-The Molecular Structure and Properties-Part 2.Molecules (Basel, Switzerland) · 2026Review
- Iodine-Substituted Dithiocarbamic Flavanones-A Structure-Activity Relationship Study of Their Antioxidant Properties.Molecules (Basel, Switzerland) · 2025Article
- Novel Dithiocarbamic Flavanones with Antioxidant Properties-A Structure-Activity Relationship Study.International journal of molecular sciences · 2024Article
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Authors and funding
2 authors.
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Abstract
The antioxidant properties of 3-dithiocarbamic flavanones have been investigated. The influence of the halogen substituents on ring A of the flavanones and the nature of the secondary amine from the dithiocarbamic moiety have been accounted. The results indicated that the presence of a halogen substituent at the C-8 position of the benzopyran ring induce better antioxidant properties against DPPH and ABTS than butylated hydroxytoluene (BHT) and ascorbic acid. The presence of a halogen substituent at the mentioned position appears to induce a higher stability for a free radical intermediate at the C-3 position of the benzopyran ring. A free radical enolate is most likely to be involved in the antioxidant activity of this dithiocarbamic flavanone. It is a stable intermediate that supports the influence of dithiocarbamic moiety on the antioxidant properties of the reported flavanones.
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