Evidence map›Paper›PMID 39199150›Full record

ArticleAntioxidants (Basel, Switzerland)2024

Astaxanthin Supplementation Does Not Alter Training-Related Changes in Inflammatory Cytokine Profile in Arabian Racing Horses.

Beata Giercuszkiewicz-Hecold, Marek Kulka, Michał Czopowicz, Ewa Szarska, Katarzyna Strzelec, Arkadiusz Grzeczka, Szymon Graczyk, Marta Wiśniewska, Zofia Jędrzejkowska, Aleksandra Rumińska and 2 more

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Beata Giercuszkiewicz-HecoldDoctoral School, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.
Marek KulkaDepartment of Pathology and Veterinary Diagnostics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.
Michał CzopowiczDivision of Veterinary Epidemiology and Economics, Institute of Veterinary Medicine, Warsaw University of Life Sciences-SGGW, Nowoursynowska 159c, 02-776 Warsaw, Poland.ORCID 0000-0002-4238-8360
Ewa SzarskaMilitary Institute of Hygiene and Epidemiology, Kozielska 4, 01-001 Warsaw, Poland.
Katarzyna StrzelecDepartment of Horse Breeding and Use, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland.ORCID 0000-0001-6460-2842
Arkadiusz GrzeczkaStudent of the Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.ORCID 0000-0001-8926-5678
Szymon GraczykStudent of the Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.ORCID 0000-0002-0228-8541
Marta WiśniewskaStudent of the Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.
Zofia JędrzejkowskaStudent of the Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.
Aleksandra RumińskaStudent of the Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Toruń, Lwowska 1, 87-100 Toruń, Poland.
Krzysztof MaryczInternational Institute of Translational Medicine, Jesionowa 11, Malin, 55-114 Wisznia Mała, Poland.
Anna CywińskaDepartment of Basic and Preclinical Sciences, Faculty of Biological and Veterinary Sciences, Nicolaus Copernicus University in Torun, Lwowska 1, 87-100 Toruń, Poland.ORCID 0000-0002-5365-9218

Funding

This research was partially funded by the state budget funds allocated by the Minister of Education and Science under the program "Student Scientific Clubs Create Innovations" project No. SKN/SP/570330/2023
6 · The paper itself

Abstract

This study aimed to evaluate the oral supplementation of astaxanthin (ATX) on inflammatory markers in 3-year-old Arabian racehorses. Despite the recognized antioxidant and anti-inflammatory properties of ATX observed in vitro in rodent models and in human athletes, the effects in equine subjects remain unknown. This study involved a controlled trial with 14 horses receiving either ATX (six horses) or a placebo (eight horses), monitored over four months of race training. Inflammatory cytokines: TNFα, IFNγ, IL-6, IL-10, and prostaglandin E (PGE), were measured monthly to assess the impact of ATX on the inflammatory response. The results indicated no significant differences in measured parameters between the ATX and the control group during the study. However, a significant time-dependent decrease in TNFα and IFNγ levels (

Indexed as

anti-inflammatory stateastaxanthincytokineshorserace training

Identifiers

PMID39199150
PMCPMC11351528

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.