Evidence map›Paper›PMID 39198914›Full record

ArticleImplementation science communications2024

A qualitative study identifying implementation strategies using the i-PARIHS framework to increase access to pre-exposure prophylaxis at federally qualified health centers in Mississippi.

Trisha Arnold, Laura Whiteley, Kayla K Giorlando, Andrew P Barnett, Ariana M Albanese, Avery Leigland, Courtney Sims-Gomillia, A Rani Elwy, Precious Patrick Edet, Demetra M Lewis and 2 more

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Article in Implementation science communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Trisha ArnoldDepartment of Psychiatry, Rhode Island Hospital, One Hoppin Street, Coro West, 204, Providence, RI, 02903, USA. trisha_arnold@brown.edu.ORCID http://orcid.org/0000-0003-3556-5717
Laura WhiteleyDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Kayla K GiorlandoDepartment of Psychiatry, Rhode Island Hospital, One Hoppin Street, Coro West, 204, Providence, RI, 02903, USA.
Andrew P BarnettDepartment of Psychiatry, Rhode Island Hospital, One Hoppin Street, Coro West, 204, Providence, RI, 02903, USA.
Ariana M AlbaneseDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Avery LeiglandDepartment of Psychiatry, Rhode Island Hospital, One Hoppin Street, Coro West, 204, Providence, RI, 02903, USA.
Courtney Sims-GomilliaDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA.
A Rani ElwyDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Precious Patrick EdetDepartment of Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA.
Demetra M LewisDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
James B BrockDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.
Larry K BrownDepartment of Psychiatry, Rhode Island Hospital, One Hoppin Street, Coro West, 204, Providence, RI, 02903, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
Telemedicine for PrEP throughout Mississippi (Tele-PrEP-MS)R34MH115744 · NIMH · RHODE ISLAND HOSPITAL · PI BROCK, JAMES BENJAMIN, BROWN, LARRY K · 2018 to 2020
$1.3M
Improving HIV Prevention Through a Psychological Flexibility-Based ApproachK23MH124539 · NIMH · RHODE ISLAND HOSPITAL · PI ARNOLD, TRISHA · 2021 to 2025
$969k
HSRD VA IK6 HX003765NIAID NIH HHS P30 AI042853NIMH NIH HHS K23 MH124539NIMH NIH HHS L30 MH123946NIMH NIH HHS R25 MH083620NIMH NIH HHS R34 MH115744
6 · The paper itself

Abstract

backgroundMississippi (MS) experiences disproportionally high rates of new HIV infections and limited availability of pre-exposure prophylaxis (PrEP). Federally Qualified Health Centers (FQHCs) are poised to increase access to PrEP. However, little is known about the implementation strategies needed to successfully integrate PrEP services into FQHCs in MS. PURPOSE: The study had two objectives: identify barriers and facilitators to PrEP use and to develop tailored implementation strategies for FQHCs.

methodsSemi-structured interviews were conducted with 19 staff and 17 PrEP-eligible patients in MS FQHCs between April 2021 and March 2022. The interview was guided by the integrated-Promoting Action on Research Implementation in Health Services (i-PARIHS) framework which covered PrEP facilitators and barriers. Interviews were coded according to the i-PARIHS domains of context, innovation, and recipients, followed by thematic analysis of these codes. Identified implementation strategies were presented to 9 FQHC staff for feedback.

resultsData suggested that PrEP use at FQHCs is influenced by patient and clinic staff knowledge with higher levels of knowledge reflecting more PrEP use. Perceived side effects are the most significant barrier to PrEP use for patients, but participants also identified several other barriers including low HIV risk perception and untrained providers. Despite these barriers, patients also expressed a strong motivation to protect themselves, their partners, and their communities from HIV. Implementation strategies included education and provider training which were perceived as acceptable and appropriate.

conclusionsThough patients are motivated to increase protection against HIV, multiple barriers threaten uptake of PrEP within FQHCs in MS. Educating patients and providers, as well as training providers, are promising implementation strategies to overcome these barriers.

Indexed as

HIV PreventionImplementation SciencePre-exposure prophylaxis (PrEP)Telemedicine

Identifiers

PMID39198914
PMCPMC11350989

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.