Evidence map›Paper›PMID 39198818›Full record

ArticleBMC endocrine disorders2024

Significance of measuring anthropometric and atherogenic indices in patients with polycystic ovary syndrome.

Emre Uysal, Omer Tammo, Esra Soylemez, Mehmet Incebıyık, Dilber Filiz, Mesut Alci

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Article in BMC endocrine disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emre UysalDepartment of Gynecology and Obstetrics, Yusufeli State Hospital, Yusufeli, Artvin, 08800, Turkey. emreuysal53@gmail.com.
Omer TammoDepartment of Gynecology and Obstetrics, Mardin Training and Research Hospital, Mardin, 47000, Turkey.
Esra SoylemezDepartment of Gynecology and Obstetrics, Mardin Training and Research Hospital, Mardin, 47000, Turkey.
Mehmet IncebıyıkDepartment of Gynecology and Obstetrics, Sanlıurfa Training and Research Hospital, Sanlıurfa, 63000, Turkey.
Dilber FilizDepartment of Gynecology and Obstetrics, Mardin Training and Research Hospital, Mardin, 47000, Turkey.
Mesut AlciDepartment of Gynecology and Obstetrics, Giresun Gynecology and Pediatrics Training and Research Hospital, Giresun, 28000, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is a prevalent hormonal disorder affecting 5-15% of women of reproductive age, characterized by ovulatory dysfunction, hyperandrogenism, and polycystic ovarian morphology. PCOS is associated with metabolic disturbances such as dyslipidemia, insulin resistance (IR), and an increased risk of type 2 diabetes (T2DM) and cardiovascular disease.

objectiveThe aim of this study is to apply new anthropometric indices [body adiposity index (BAI), visceral adiposity Index (VAI), lipid accumulation product (LAP), body roundness index (BRI), a body shape index (ABSI)] and new atherogenic indices [Castelli index-I, Castelli index-II, atherogenic risk of plasma (AIP), atherogenic coefficient (AC), lipoprotein combined index (LCI), triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) ratio, metabolic score for insulin resistance (METS-IR), triglyceride glucose (TyG) index, triglyceride glucose-dody mass (TyG-BMI) index, triglyceride glucose-waist circumference (TyG-WC) index] metabolic score of insulin resistance to patients with PCOS.

methodsA retrospective analysis was conducted on 248 women diagnosed with PCOS based on the 2003 Rotterdam criteria. Anthropometric measurements, biochemical parameters, and atherogenic indices were collected from patient records. Statistical analyses were performed using Statistical Package for the Social Sciences software version 28.0.

resultsSignificant correlations were found between fasting glucose and various anthropometric indices, such as Body mass index (BMI), waist-height ratio (WHtR), and BAI, indicating a link between adiposity and glucose metabolism in PCOS. Atherogenic indices like Castelli's risk indices, AIP, and AC showed positive correlations with glucose and insulin levels, reinforcing their role in assessing cardiovascular risk. Novel indices such as METS-IR and TyG demonstrated strong correlations with both glucose and insulin profiles, highlighting their potential as reliable markers for IR and cardiometabolic risk.

conclusionThe study underscores the importance of using a range of anthropometric and atherogenic indices for comprehensive metabolic assessment in women with PCOS. Indices like METS-IR and TyG offer valuable insights into insulin sensitivity and cardiovascular risk, potentially aiding in better management and prognosis of PCOS.

Indexed as

AnthropometryAtherosclerosisInsulin ResistancePolycystic Ovary SyndromeAdiposityAdultBody Mass IndexFemaleHumansPrognosisRetrospective StudiesWaist CircumferenceYoung AdultAnthropometryAtherogenic indicesCardiometabolic riskInsulin resistanceMetabolic indicesPCOS

Identifiers

PMID39198818
PMCPMC11351255

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.