Evidence map›Paper›PMID 39198782›Full record

ArticleBMC cardiovascular disorders2024

A morphological indicator for aortic dissection: fitting circle of the thoracic aorta.

Hongji Pu, Tao Peng, Zhijue Xu, Qi Sun, Zixin Wang, Hui Ma, Shu Fang, Yang Yang, Jie Wu, Ruihua Wang and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hongji Pu *Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Tao Peng *School of Biomedical Engineering, Anhui Medical University, Meishan Road, Shushan District, Hefei, 230032, China.
Zhijue Xu *Department of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Qi SunDepartment of Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Zixin WangSchool of Biomedical Engineering, Anhui Medical University, Meishan Road, Shushan District, Hefei, 230032, China.
Hui MaSchool of Biomedical Engineering, Anhui Medical University, Meishan Road, Shushan District, Hefei, 230032, China.
Shu FangSchool of Biomedical Engineering, Anhui Medical University, Meishan Road, Shushan District, Hefei, 230032, China.
Yang YangDepartment of Computer Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Jie WuDepartment of Vascular Surgery, Affiliated Hospital of Guizhou Medicine University, Guizhou, 550000, China.
Ruihua WangDepartment of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.
Peng QiuDepartment of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. hiiigh@163.com.
Jinhua ZhouSchool of Biomedical Engineering, Anhui Medical University, Meishan Road, Shushan District, Hefei, 230032, China. zhoujinhua@ahmu.edu.cn.
Xinwu LuDepartment of Vascular Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China. luxinwu@shsmu.edu.cn.

Funding

Society for Epidemiologic Research Doctoral Dissertation WorkshopR13TR002021 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HARLOW, BERNARD L · 2017 to 2018
$46k
Clinical Research Plan of SHDC SHDC2020CR6016-003Natural Science Foundation of Anhui Provincial Education Department KJ2021A0251Shanghai Jiao Tong University School of Medicine Doctoral Innovation Fund BXJ201935Shanghai Ninth People's Hospital Nursing Fund Project JYHL2020MS01Translational Medicine Science and Technology Infrastructure Opening Project TMSK-2021-121
6 · The paper itself

Abstract

backgroundThis study aims to identify a morphological indicator of aortic dissection (AD) based on the geometrical characteristics of the thoracic aorta.

methodsWe evaluated computed tomographic angiograms of 63 samples with AD (22 with type A AD, 41 with type B AD) and 71 healthy samples. Via centerline extraction and spatial transformation, the spatial entanglement of the aorta was minimized, and the expanded 2D aortic morphology was obtained. The 2D morphology of the thoracic aorta was fit to a circle. The applicability of the fitting circle method for identifying aortic dissection was verified by multivariable logistic regression analysis.

resultsVia the 3D coordinate transformation algorithm, the optimal aortic view was obtained. On this view, the geometrical characteristics of the thoracic aortas of the healthy controls were similar to a portion of a circle (sum of residuals: 3502.45 ± 2566.71, variance: 86.23 ± 56.60), while that of AD samples had poorer similarity to the circle (sum of residuals: 5404.78 ± 3891.69, variance: 129.90 ± 90.09). This difference was significant (p < 0.001). A logistic regression model showed that increased deformation of the thoracic aorta was a significant indicator of aortic dissection (odds ratio: 1.35, p = 0.034).

conclusionsThe morphology of the healthy thoracic aorta could be fit to a circle, while that of the dissected aorta had poorer similarity to the circle. The statistics of the circle are an effective indicator of aortic deformation in AD.

trial registrationThis study is registered in the Chinese Clinical Trial Registry (ChiCTR2000029219).

Indexed as

Aorta, ThoracicAortic Aneurysm, ThoracicAortic DissectionAortographyComputed Tomography AngiographyPredictive Value of TestsRadiographic Image Interpretation, Computer-AssistedAdultAgedCase-Control StudiesFemaleHumansMaleMiddle AgedMultidetector Computed TomographyRetrospective StudiesAlgorithmAortic dissectionComputed tomographic angiographyDiagnostic imagingGeometrical analysis

Identifiers

PMID39198782
PMCPMC11351444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.