ArticleNature2024
Sympathetic neuropeptide Y protects from obesity by sustaining thermogenic fat.
Abstract read
In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Influence of the argon plasma coagulation protocol in endoscopic procedures on body composition in patients with recurrent weight gain after Roux-en-Y gastric bypass: a randomized clinical trial.Surgical endoscopy · 2026Trial
- A non-invasive method for light-inducible knockout across all cell types in mouse subcutaneous adipose tissue.Adipocyte · 2026Article
- Effects of 6-OHDA-Mediated Chemical Denervation of Sympathetic Axons in Inguinal Subcutaneous White Adipose Tissue.Diabetes, obesity & metabolism · 2026Article
- Adipose tissue as a humoral-neuronal hub in metabolic regulation.Nature reviews. Endocrinology · 2026Review
- Peripheral Neuropathy in Metabolic Stress.International journal of molecular sciences · 2026Review
- Neural regulation of cancer: from microenvironmental hijacking to systemic circuit co-option.Cellular oncology (Dordrecht, Netherlands) · 2026Review
- Article
- The perineurium integrates leptin with its sympathetic outflow to protect against obesity.Nature metabolism · 2026Article
- Circuit organization and transcriptomic heterogeneity of sympathetic circuits innervating cranial structures.Cell reports · 2026Article
- Pro-neuropeptide Y as a circulating biomarker for poor prognosis in prostate cancer.Scientific reports · 2026Article
- Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure.Current obesity reports · 2026Review
- WAT-to-BAT communication facilitates the sustained activation of BAT thermogenesis during cold exposure.Cell discovery · 2026Article
- Neural regulation of bone: from central neural circuits to peripheral innervation of the skeletal stem cell niche.Bone research · 2026Review
- Multimodal, device-based therapeutic targeting of the cardiovascular autonomic nervous system.Nature reviews. Cardiology · 2026Review
- Two roads to thermogenesis: vascular and parenchymal sympathetic innervation of brown adipose tissue.Nature reviews. Endocrinology · 2026Article
- Single cell transcriptomics of human weight loss links adipocyte NPY1R to control of lipolysis.Molecular metabolism · 2026Article
- Distinct sympathetic projections to brown fat regulate thermogenesis and glucose tolerance.Nature metabolism · 2026Article
- Heterogeneous sympathetic control of brown adipose tissue.Nature metabolism · 2026Article
- Advances in Adipose Tissue Biology.Endocrine reviews · 2026Review
- Sympathetic regulation of bone homeostasis and remodeling: molecular mechanisms, pathophysiological roles, and therapeutic implications.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Yitao ZhuDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Lu YaoDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Ana L Gallo-FerrazLaboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil.
Bruna BombassaroLaboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil.
Marcela R SimõesLaboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil.
Ichitaro AbeBeth Israel Deaconess Medical Center, Division of Endocrinology, Diabetes & Metabolism, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2769-5338
Jing ChenSchool of Sport Science, Beijing Sport University, Beijing, China.ORCID 0000-0003-1894-335X
Gitalee SarkerDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Alessandro CiccarelliAdvanced Light Microscopy, The Francis Crick Institute, London, UK.ORCID 0000-0002-7612-8161
Linna ZhouLudwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-1938-5428
Carl LeeKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.
Davi Sidarta-OliveiraDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Noelia Martínez-SánchezOxford Centre for Diabetes, Endocrinology and Metabolism Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-4580-8196
Michael L DustinKennedy Institute of Rheumatology, University of Oxford, Oxford, UK.ORCID 0000-0003-4983-6389
Cheng ZhanDepartment of Haematology, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.ORCID 0000-0001-9397-0871
Tamas L HorvathDepartment of Obstetrics/Gynecology and Reproductive Sciences, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-7522-4602
Licio A VellosoLaboratory of Cell Signaling, Obesity and Comorbidities Research Center, University of Campinas, Campinas, Brazil.ORCID 0000-0002-4806-7218
Shingo KajimuraBeth Israel Deaconess Medical Center, Division of Endocrinology, Diabetes & Metabolism, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-0672-5910
Ana I DomingosDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. ana.domingos@dpag.ox.ac.uk.ORCID 0000-0002-7938-4814
Funding
The next iteration of the AMP-T2D Knowledge PortalUM1DK105554 · NIDDK · BROAD INSTITUTE, INC. · PI BOEHNKE, MICHAEL L, BURTT, NOEL P · 2020 to 2025
$18.5MP&F programP30DK135043 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Aaron S Leong · 2023 to 2026
$5.4MCalRepository: A database of indirect calorimetry experiments for the study of energy homeostasisR01DK133948 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BANKS, ALEXANDER · 2022 to 2025
$2.0MNIDDK NIH HHS P30 DK135043NIDDK NIH HHS R01 DK133948NIDDK NIH HHS UM1 DK105554Wellcome Trust
Abstract
Human mutations in neuropeptide Y (NPY) have been linked to high body mass index but not altered dietary patterns
Indexed as
Adipose Tissue, BrownAdipose Tissue, WhiteNeuronsNeuropeptide YObesitySympathetic Nervous SystemThermogenesisAdipocytesAnimalsAxonsBody WeightCell ProliferationDatasets as TopicDiet, High-FatEnergy MetabolismFeeding BehaviorNeuropeptide Y
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.