ArticleNature2024
Spatially clustered type I interferon responses at injury borderzones.
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In one paragraph
Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed.
- Butyrate counteracts maternal obesity-induced cardiac defects by promoting PLEKHG3-actin binding.EMBO reports · 2026Article
- Modeling the Exposome in Murine Cardiovascular Disease.JACC. Basic to translational science · 2026Review
- Type I IFN signaling shapes subset-specific monocyte fates in the injured myocardium.The Journal of clinical investigation · 2026Article
- Fate-mapping infiltrating monocytes following experimental myocardial infarction reveals differentiation trajectories in the infarcted heart.The Journal of clinical investigation · 2026Article
- Spatial isoform sequencing at single-cell resolution reveals cell-type-specific spatial isoform variability in multiple brain cell types.Nature methods · 2026Article
- Intratumoral Mycobacterium abscessus promotes cytidine deaminase mutagenesis in non-small cell lung cancer.Signal transduction and targeted therapy · 2026Article
- Macrophage adenylyl cyclase 7 protects against myocardial ischemia/reperfusion injury in male mice.Nature communications · 2026Article
- Trimodal, uncertainty-guided whole-slide framework for genome-scale spatial expression and image-only virtual perturbation in cancer cohorts.Genome medicine · 2026Article
- TNF-α induces type I IFN signalling to suppress neurogenesis and recruit T cells.Nature communications · 2026Article
- Macrophages and the Survival of Cardiomyocytes After Myocardial Infarction.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Infusible Extracellular Matrix Biomaterial Enhances Cell-Specific Pro-Repair Responses Following Acute Myocardial Infarction.Advanced healthcare materials · 2026Article
- Spatial and Single-Cell Mapping Reveals Valvular Interstitial Cell and Macrophage Sex Differences in Calcific Aortic Valve Disease.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- Spatial transcriptomic profiling of developing mouse hearts reveals a spatially patterned signaling environment.Communications biology · 2026Article
- Beyond Reperfusion: Early Molecular Drivers and Therapeutic Opportunities in Acute Post-Infarction Cardiac Fibrosis.International journal of molecular sciences · 2026Review
- Spatial imprints of emergent cardiomyocyte states in the pressure-overloaded heart.bioRxiv : the preprint server for biology · 2026Article
- Microfluidic Modeling of Macrophage-Induced Cardiac Inflammation Using NF-κB Reporter Cardiomyocytes.Advanced healthcare materials · 2026Article
- Multiomics immune profiling of a patient-relevant orthotopic lung cancer model using SEPARATE-Seq.Nature communications · 2026Article
- METTL14-dependent mbioRxiv : the preprint server for biology · 2026Article
- TransientCirculation · 2026Article
- Spatial and Functional Immune Profiling Identifies Impaired Vascular Repair in Human Myocardial Infarction.Biomedicines · 2026Article
Corrections and comments
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Authors and funding
18 authors.
V K Ninh *Division of Cardiology and Cardiovascular Institute, Department of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-6017-4035
D M Calcagno *Department of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
J D YuDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
B ZhangDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
N TaghdiriDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
R SehgalDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-3609-7452
J M MesfinDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0003-1022-8175
C J ChenDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
K KalhorDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-9416-3078
A ToomuDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
J M DuranDivision of Cardiology and Cardiovascular Institute, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
E AdlerDivision of Cardiology and Cardiovascular Institute, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
J HuDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.
K ZhangDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-7596-5224
K L ChristmanDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-6179-898X
Z FuDivision of Cardiology and Cardiovascular Institute, Department of Medicine, University of California San Diego, La Jolla, CA, USA.
B BintuDepartment of Bioengineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
K R KingDivision of Cardiology and Cardiovascular Institute, Department of Medicine, University of California San Diego, La Jolla, CA, USA. krking@ucsd.edu.ORCID 0000-0003-1472-2189
Funding
UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3MTraining In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1MIntegrative Bioengineering of Heart, Vessels, and BloodT32HL105373 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, INTAGLIETTA, MARCOS · 2010 to 2019
$3.6MElucidating Cell Communication Networks during Tissue Inflammation, Fibrosis, and RegenerationDP2AR075321 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KING, KEVIN R · 2018 to 2018
$2.4MHigh-throughput imaging of 3D chromatin regulation events in the nervous systemDP5OD031878 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BINTU, BOGDAN · 2021 to 2025
$2.0MDanger Signaling and Spread of Injury after Myocardial InfarctionR00HL129168 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI KING, KEVIN R · 2017 to 2019
$746kIllumina NovaSeq 6000 Sequencing SystemS10OD026929 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JEPSEN, KRISTEN LYNN · 2019 to 2019
$600kNCATS NIH HHS UL1 TR001442NHLBI NIH HHS R00 HL129168NHLBI NIH HHS T32 HL007444NHLBI NIH HHS T32 HL105373NIAMS NIH HHS DP2 AR075321NIH HHS DP5 OD031878NIH HHS S10 OD026929
Abstract
Sterile inflammation after myocardial infarction is classically credited to myeloid cells interacting with dead cell debris in the infarct zone
Indexed as
Interferon Type IMyocardial InfarctionAnimalsDendritic CellsEndothelial CellsFemaleFibroblastsGene Expression ProfilingHumansImmunity, InnateInterferon Regulatory Factor-3MacrophagesMaleMiceMice, Inbred C57BLMyocytes, CardiacCcr2 protein, mouseInterferon Regulatory Factor-3Interferon Type IIRF3 protein, humanIrf3 protein, mouseReceptors, CCR2
Identifiers
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.