ArticleNature immunology2024
NaCl enhances CD8
Abstract read
In one paragraph
Article in Nature immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of CD8Frontiers in immunology · 2026Pooled it
- Sex-dependent modulation of T and NK cells and gut microbiome by low sodium diet in patients with primary aldosteronism.Frontiers in immunology · 2024Trial
- Killing cancer takes guts: lessons learned from the manipulation of gut microbiome and immunotherapy for the future of urothelial carcinoma.Oncoimmunology · 2026Review
- Glutamate attenuates the ILC2 response and allergic airway inflammation via the kainate receptor GluK2.Cellular & molecular immunology · 2026Article
- Bispecific ANXA2/CD147 CAR-T cell therapy for osteosarcoma.Oncogene · 2026Article
- Metabolic profiling of CAR T-cells in patients reveals a shift toward amino acid-supported OXPHOS and informs transporter engineering.Research square · 2026Article
- γδ T cells in colorectal and liver cancer.Nature reviews. Gastroenterology & hepatology · 2026Review
- Unraveling the role of glutamine metabolism in cancer: from cell death mechanisms to tumor microenvironment modulation.Experimental hematology & oncology · 2026Review
- VSIG4 suppresses antitumor T cell immunity via the SLC3A2-dependent metabolic-ionic checkpoint.Journal for immunotherapy of cancer · 2026Article
- Amino Acids as Targets for Immunotherapy against Solid Tumors.Cell biochemistry and biophysics · 2026Review
- Potassium suppresses allosteric activation of ZAP-70-dependent T cell receptor signaling.The Journal of biological chemistry · 2026Article
- "Ferroptosis-immune" cycle: Research progress of tumor microenvironment responsive nanomaterials in the treatment of pancreatic cancer.iScience · 2026Review
- Development and validation of nomograms integrating electrolyte, nutritional, and inflammatory indicators to predict survival in advanced esophageal cancer undergoing immunotherapy or radioimmunotherapy.Journal of thoracic disease · 2026Article
- Inducible secretion of LIGHT by engineered probiotics enables localized cytokine therapy and robust antitumor immunity.RSC advances · 2026Article
- Single-cell-based identification of drug synergy with immunotherapy via tumor microenvironment remodeling.Journal for immunotherapy of cancer · 2026Article
- IL-21 enhances the cytotoxicity of intratumoral CD8+ T cells, improving radiation efficacy.JCI insight · 2026Article
- Metal fluoride nanoregulators reverse therapeutic resistance via stemness remodeling to trigger pyroptosis for chemoimmunotherapy.Bioactive materials · 2026Article
- Regulators of CD8Nature reviews. Immunology · 2026Review
- Probiotic-inspired hybrid nanovesicles for enhancing immune checkpoint therapy efficiency via tumor immune microenvironment modulation.Bioactive materials · 2026Article
- Transcriptomic Analysis Reveals Novel Mechanisms Underlying Neutrophil Activation Induced by High Salt.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
33 authors.
Caterina Scirgolea *IRCCS Humanitas Research Hospital, Milan, Italy.
Rosa Sottile *IRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0003-2950-9508
Marco De LucaIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0001-8310-5526
Alberto SusanaIRCCS Humanitas Research Hospital, Milan, Italy.
Silvia CarnevaleIRCCS Humanitas Research Hospital, Milan, Italy.
Simone PuccioIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0003-4007-4365
Valentina FerrariIRCCS Humanitas Research Hospital, Milan, Italy.
Veronica LiseIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0001-7978-4837
Giorgia ContariniIRCCS Humanitas Research Hospital, Milan, Italy.
Alice ScarpaIRCCS Humanitas Research Hospital, Milan, Italy.
Eloise ScamardellaIRCCS Humanitas Research Hospital, Milan, Italy.
Simona FenoIRCCS Humanitas Research Hospital, Milan, Italy.
Chiara CamisaschiIRCCS Humanitas Research Hospital, Milan, Italy.
Gabriele De SimoneIRCCS Humanitas Research Hospital, Milan, Italy.
Gianluca BassoIRCCS Humanitas Research Hospital, Milan, Italy.
Desiree GiulianoIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0003-0576-4125
Emilia Maria Cristina MazzaIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0003-2424-3640
Luca GattinoniDivision of Functional Immune Cell Modulation, Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany.ORCID http://orcid.org/0000-0003-2239-3282
Rahul RoychoudhuriDepartment of Pathology, University of Cambridge, Cambridge, UK.
Emanuele VoulazDepartment of Biomedical Sciences, Humanitas University, Milan, Italy.
Diletta Di MitriIRCCS Humanitas Research Hospital, Milan, Italy.
Matteo SimonelliIRCCS Humanitas Research Hospital, Milan, Italy.
Agnese LosurdoIRCCS Humanitas Research Hospital, Milan, Italy.
Davide PozziIRCCS Humanitas Research Hospital, Milan, Italy.
Carlson TsuiThe Peter Doherty Institute for Infection and Immunity and Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0003-0642-814X
Axel KalliesThe Peter Doherty Institute for Infection and Immunity and Department of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australia.ORCID http://orcid.org/0000-0002-6312-6968
Sara TimoIRCCS Humanitas Research Hospital, Milan, Italy.
Giuseppe MartanoIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-5963-4580
Elettra BarberisDepartment of Sciences and Technological Innovation, University of Piemonte Orientale, Alessandria, Italy.
Marcello ManfrediDepartment of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Maria RescignoIRCCS Humanitas Research Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-6464-509X
Sebastien JaillonIRCCS Humanitas Research Hospital, Milan, Italy.
Enrico LugliIRCCS Humanitas Research Hospital, Milan, Italy. enrico.lugli@humanitasresearch.it.ORCID http://orcid.org/0000-0002-1964-7678
Funding
Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) AIRC 5×1000 program UniCanVax 22757Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) AIRC/FIRC fellowshipAssociazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) AIRC IG 2017 - ID 20676Associazione Italiana per la Ricerca sul Cancro (Italian Association for Cancer Research) AIRC IG 2022 - ID 27391Cancer Research Institute (CRI) CRI Lloyd J. Old STAR (CRI award 3914)
Abstract
CD8
Indexed as
CD8-Positive T-LymphocytesImmunotherapySodium ChlorideAnimalsCell DifferentiationCell Line, TumorGlutamineHumansImmunotherapy, AdoptiveInterferon-gammaMiceMice, Inbred C57BLNeoplasmsTumor MicroenvironmentGlutamineInterferon-gammaSodium Chloride
Identifiers
PMID
39198631What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.