ArticleTranslational psychiatry2024
Association patterns of antisocial personality disorder across substance use disorders.
Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Personality Functioning and Antisociality of Youth Accessing Residential Substance Use Withdrawal in Australia.Drug and alcohol review · 2026Article
- A nomogram model to predict the risk for etomidate use disorder with antisocial personality disorder.BMC psychiatry · 2026Article
- Decoding the bidirectional links between alcohol misuse and aggression: toward a unified translational framework.Psychopharmacology · 2026Review
- Participant ascertainment is differentially related to phenotypic characteristics and alcohol-related genetic liability in a sample with severe alcohol use disorder.Alcohol, clinical & experimental research · 2026Article
- Why Do They Do It? The Psychology Behind Antisocial Behavior in Children and Adolescents.Pediatric reports · 2025Review
- Psychological, social factors, and smoking behavior mediated the effects of cannabis use on personality disorders: A Mendelian randomization study.Frontiers in psychiatry · 2025Article
- Clinical characteristics of adults with alcohol dependence syndrome comorbid with antisocial personality disorder: a cross-sectional study.Frontiers in psychiatry · 2024Article
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Abstract
There is a high prevalence of antisocial personality disorder (ASPD) in individuals affected by substance use disorders (SUD). However, there is limited information on the specific patterns of association of ASPD with SUD severity and specific SUD diagnostic criteria. We investigated the association of alcohol, cannabis, cocaine, opioid, and tobacco use disorders (AUD, CanUD, CocUD, OUD, and TUD, respectively) in 1660 individuals with ASPD and 6640 controls matched by sex (24% female), age, and racial/ethnic background in a sample ascertained for addiction-related traits. Generalized linear regressions were used to test ASPD with respect to the five DSM-5 SUD diagnoses, their severity (i.e., mild, moderate, severe), and their diagnostic criteria. We found that ASPD is associated with the diagnosis and severity of AUD (Odds Ratio, ORs = 1.89 and 1.25), CanUD (ORs = 2.13 and 1.32), and TUD (ORs = 1.50 and 1.21) (ps < 0.003). Of the specific diagnostic criteria, the "hazardous use" criterion showed the strongest association with ASPD across the five SUDs investigated (from OR
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