Evidence map›Paper›PMID 39198369›Full record

GuidelineLa Radiologia medica2024

Prevention and management of radiotherapy-related toxicities in gynecological malignancies. Position paper on behalf of AIRO (Italian Association of Radiotherapy and Clinical Oncology).

Elisabetta Perrucci, Gabriella Macchia, Annamaria Cerrotta, Angela Damiana Andrulli, Rosa Autorino, Amelia Barcellini, Maura Campitelli, Giulia Corrao, Sara Costantini, Vitaliana De Sanctis and 19 more

Abstract readPractice Guideline
In one paragraph

Guideline in La Radiologia medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Gut · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Elisabetta PerrucciRadiation Oncology Section, Perugia General Hospital, Perugia, Italy.
Gabriella MacchiaRadiation Oncology Unit, Responsible Research Hospital, Campobasso, Italy.
Annamaria CerrottaRadiotherapy Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milan, Italy.
Angela Damiana AndrulliRadiotherapy Unit, Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy.
Rosa AutorinoUOC di Radioterapia, Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Amelia BarcelliniRadiation Oncology Unit, Clinical Department, CNAO National Center for Oncological Hadrontherapy, Pavia, Italy.
Maura CampitelliUOC di Radioterapia, Dipartimento di Scienze Radiologiche, Radioterapiche ed Ematologiche, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.
Giulia CorraoDepartment of Radiotherapy, IEO European Institute of Oncology IRCCS, Milan, Italy.
Sara CostantiniRadiation Oncology Centre, Santa Maria Hospital, Terni, Italy.
Vitaliana De SanctisRadiotherapy Oncology, Department of Medicine, Surgery and Translational Medicine, St. Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Jacopo Di MuzioDipartimento Di Oncologia P.O. S. Anna - SS Radioterapia, A.O.U "Città Della Salute E Della Scienza", Turin, Italy.
Valeria EpifaniRadiation Oncology Section, University of Perugia, Perugia, Italy. valeria.epifani@ospedale.perugia.it.ORCID http://orcid.org/0009-0007-1172-3246
Patrizia FerrazzaUO Radioterapia Oncologica, Ospedale S. Chiara, Trento, Italy.
Andrei FodorDepartment of Radiation Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elisabetta GaribaldiDepartment of Radiotherapy, Ospedale Regionale Parini-AUSL Valle d'Aosta, Aosta, Italy.
Concetta LalisciaDepartment of Translational Medicine, Radiation Oncology Division, University of Pisa, Pisa, Italy.
Roberta LazzariDepartment of Radiotherapy, IEO European Institute of Oncology IRCCS, Milan, Italy.
Elena MagriDepartment of Radiotherapy, Santa Chiara Hospital, Trento, Italy.
Cristina MariucciRadiotherapy Department, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy.
Maria Paola PaceUOC Radioterapia Oncologica, Ospedale Generale Provinciale di Macerata, AST Macerata, Italy.
Brigida PappalardiRadiotherapy Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
Alice PastorinoRadiotherapy, A.O.SS. Antonio e Biagio, Alessandria, Italy.
Federica PiccoloRadiotherapy Unit, Ospedale di Circolo Fondazione Macchi, Varese, Italy.
Claudio ScoglioRadiotherapy Unit, Ospedale Maggiore di Trieste, Trieste, Italy.
Alessia SurgoDepartment of Radiation Oncology, General Regional Hospital "F. Miulli", Acquaviva delle Fonti, Bari, Italy.
Francesca TitoneRadiation Oncology Unit, Department of Oncology, "Santa Maria della Misericordia" University Hospital, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy.
Francesca TortoretoU.O.C. Radiotherapy, Ospedale Isola Tiberina - Gemelli Isola, Rome, Italy.
Francesca De FeliceDepartment of Radiotherapy, Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Rome, Italy.
Cynthia AristeiRadiation Oncology Section, University of Perugia and Perugia General Hospital, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multi-modal therapies for gynecological cancers management may determine a wide range of side effects which depend on therapy-related factors and patient characteristics and comorbidities. Curative or adjuvant pelvic radiotherapy is linked with acute and late toxicity due to irradiation of organs at risk, as small and large bowel, rectum, bladder, pelvic bone, vagina and bone marrow. Successful toxicity management varies with its severity, Radiation Centre practice and experience and skills of radiation oncologists. This position paper was designed by the Italian Association of Radiation and Clinical Oncology Gynecology Study Group to provide radiation oncologists with evidence-based strategies to prevent and manage acute and late toxicities and follow-up recommendations for gynecological cancer patients submitted radiotherapy. Six workgroups of radiation oncologists with over 5 years of experience in gynecologic cancers were setup to investigate radiotherapy-related toxicities. For each topic, PubMed database was searched for relevant English language papers from January 2005 to December 2022. Titles and abstracts of results were checked to verify suitability for the document. Reference lists of selected studies and review papers were added if pertinent. Data on incidence, etiopathogenesis, prevention, treatment and follow-up of acute and late side effects for each organ at risk are presented and discussed.

Indexed as

Genital Neoplasms, FemaleRadiation InjuriesFemaleHumansItalyOrgans at RiskRadiation OncologyRadiotherapySocieties, MedicalAcute late toxicityFollow-upGynecological cancersPreventionRadiotherapyTreatment

Identifiers

PMID39198369
PMCPMC11379782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.