Evidence map›Paper›PMID 39198164›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Coexistence of Sjögren's Syndrome-associated Interstitial Nephritis and Hypokalemic Nephropathy in a Patient with Distal Renal Tubular Acidosis.

Rena Matsui, Maika Gojo, Kohei Odajima, Shinichiro Asakawa, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Satoe Numakura, Yasutoshi Oshima, Ryuji Ohashi and 2 more

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In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rena MatsuiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Maika GojoDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Kohei OdajimaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shinichiro AsakawaDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Shigeyuki AraiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Osamu YamazakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshifuru TamuraDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Satoe NumakuraDepartment of Pathology, Teikyo University Hospital, Japan.
Yasutoshi OshimaDepartment of Pathology, Teikyo University Hospital, Japan.
Ryuji OhashiDepartment of Integrated Diagnostic Pathology, Nippon Medical School, Japan.
Shigeru ShibataDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.
Yoshihide FujigakiDepartment of Internal Medicine, Teikyo University School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 42-year-old woman presented with muscle weakness and hypokalemic distal renal tubular acidosis (dRTA). Investigations revealed concurrent Sjögren's syndrome (SS) and Hashimoto's thyroiditis contributing to hypokalemic dRTA. A renal biopsy revealed focal tubulointerstitial nephritis (TIN) suggestive of SS-related renal involvement, along with distinctive ischemic glomerular changes and tubular alterations consistent with hypokalemic nephropathy. Rapid improvement in tubular injury markers and hypobicarbonemia followed potassium supplementation, suggesting that hypokalemia contributed to proximal tubular injury. This case underscores the diagnostic challenge posed by the simultaneous presence of TIN and hypokalemic nephropathy, potentially masking hypokalemic nephropathy in patients with hypokalemic dRTA secondary to SS-TIN.

Indexed as

Acidosis, Renal TubularHypokalemiaNephritis, InterstitialSjogren's SyndromeAdultFemaleHumansdistal renal tubular acidosisHashimoto's thyroiditishypokalemic nephropathySjögren's syndrometubulointerstitial nephritis

Identifiers

PMID39198164
PMCPMC12021504

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.