Evidence map›Paper›PMID 39197951›Full record

ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Transthalamic Pathways for Cortical Function.

S Murray Sherman, W Martin Usrey

Abstract readReview
In one paragraph

Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Synaptic Plasticity as a Function of the Temporal Derivative.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Modulation and Gating of Transthalamic and Subcortical Pathways through Somatosensory Thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S Murray ShermanDepartment of Neurobiology, University of Chicago, Chicago, Illinois 60637 msherman@bsd.uchicago.edu.ORCID 0000-0002-1520-2778
W Martin UsreyCenter for Neuroscience, University of California, Davis, California 95618.ORCID 0000-0002-4582-4180

Funding

VISION RESEARCH CORE GRANTP30EY012576 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 1999 to 2026
$18.9M
Thalamocortical cognitive networks in the healthy human brainP50MH132642 · NIMH · PRINCETON UNIVERSITY · PI Zhe Sage Chen · 2023 to 2026
$15.7M
Functional Properties of Neural Circuits for VisionR01EY013588 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI USREY, W MARTIN · 2001 to 2022
$7.8M
Thalamocortical interactionsR01NS094184 · NINDS · UNIVERSITY OF CHICAGO · PI Jason Neil MacLean, S. Murray SHERMAN · 2016 to 2026
$4.6M
Connectome of circuits within and between thalamus and cortexR01NS113922 · NINDS · UNIVERSITY OF CHICAGO · PI KASTHURI, NARAYANAN, SHERMAN, S. MURRAY · 2020 to 2024
$2.8M
Studies of direct and transthalamic pathways in visual cortexR01EY036242 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI S. Murray SHERMAN, W MARTIN USREY · 2024 to 2026
$2.2M
NEI NIH HHS P30 EY012576NEI NIH HHS R01 EY013588NEI NIH HHS R01 EY036242NIMH NIH HHS P50 MH132642NINDS NIH HHS R01 NS094184NINDS NIH HHS R01 NS113922
6 · The paper itself

Abstract

The cerebral cortex contains multiple, distinct areas that individually perform specific computations. A particular strength of the cortex is the communication of signals between cortical areas that allows the outputs of these compartmentalized computations to influence and build on each other, thereby dramatically increasing the processing power of the cortex and its role in sensation, action, and cognition. Determining how the cortex communicates signals between individual areas is, therefore, critical for understanding cortical function. Historically, corticocortical communication was thought to occur exclusively by direct anatomical connections between areas that often sequentially linked cortical areas in a hierarchical fashion. More recently, anatomical, physiological, and behavioral evidence is accumulating indicating a role for the higher-order thalamus in corticocortical communication. Specifically, the transthalamic pathway involves projections from one area of the cortex to neurons in the higher-order thalamus that, in turn, project to another area of the cortex. Here, we consider the evidence for and implications of having two routes for corticocortical communication with an emphasis on unique processing available in the transthalamic pathway and the consequences of disorders and diseases that affect transthalamic communication.

Indexed as

Cerebral CortexNeural PathwaysThalamusAnimalsHumanscortexefference copythalamus

Identifiers

PMID39197951
PMCPMC11358609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.